Results 211 to 220 of about 800,202 (299)

Polyproline: A Synthetic Polypeptide With Unique Properties

Angewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec, Josué M. Galindo, Colin Bonduelle, Andreas Heise   +3 more
wiley   +2 more sources

Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C-Neuroligin 3 Mouse Model of Autism Spectrum Disorder. [PDF]

J Neurochem
Meringolo M, Montanari M, D'Antoni S, Martella G, El Atiallah I, Ponterio G, Tassone A, Reverte I, Caprioli D, Strimpakos G, Pieroni L, Catania MV, Bonsi P.   +12 more
europepmc   +1 more source

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

Isolation, characterization and testing of RNA aptamers targeting glutamate receptors in a rat spinal cord injury pain model. [PDF]

Commun Biol
Jergova S, Huang Z, Lin CY, Akamatsu M, Sagen J, Niu L.   +5 more
europepmc   +1 more source

A Conserved Isoleucine Gates the Diffusion of CO and O2 to the Active Site of NiFe CO‐Dehydrogenase

Angewandte Chemie, EarlyView.
A combination of protein film electrochemistry and site‐directed mutagenesis shows that isoleucine 563 (numbering of Thermococcus sp. AM4) gates the arrival of both CO and O2 to the active site of the nickel‐iron CO dehydrogenases. Mutations at this position increase the resistance to O2 at the cost of a slower reaction with CO.
Laura Opdam, Marta Meneghello, Chloé Guendon, Jade Chargelègue, Andrea Fasano, Aurore Jacq‐Bailly, Christophe Léger, Vincent Fourmond   +7 more
wiley   +2 more sources

The Potential Role of Glutamate Receptors and their Antagonists or Modulators in Migraine Therapy. [PDF]

Curr Neuropharmacol
Tsai CH, Lai MC, Huang CW.
europepmc   +1 more source

Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors. [PDF]

Nat Commun
Ostenrath AM, Faturos N, Çiftci Çobanoğlu YI, Serneels B, Jeong I, Dongel Dayanc E, Enz A, Hinrichsen F, Mutlu AK, Bardenhewer R, Jetti SK, Neuhauss SCF, Jurisch-Yaksi N, Yaksi E.   +13 more
europepmc   +1 more source

The gating properties of Drosophila NMJ glutamate receptors and their dependence on Neto. [PDF]

J Physiol
Han TH, Vicidomini R, Ramos CI, Mayer ML, Serpe M.   +4 more
europepmc   +1 more source

Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Di Menna L, Alborghetti M, De Bartolo MI, Borro M, Gentile G, Zinni M, Bologna M, Cutrona C, D'Errico G, Imbriglio T, Bucci D, Merlo S, Ginerete RP, Orlando R, Carrillo F, Fortunato G, Cannella M, Sortino MA, Pansiot J, Baud O, Nicoletti F, Bruno V, Simmaco M, Pontieri FE, Bianchini E, Rinaldi D, de Curtis A, De Gaetano G, Iacoviello L, Esposito T, Berardelli A, Battaglia G.   +31 more
europepmc   +1 more source

Synaptic Plasticity Linked to Ionotropic Glutamate Receptors After Nicotine Exposure. [PDF]

Curr Neuropharmacol
Kazmi A, Choe ES.
europepmc   +1 more source