Results 241 to 250 of about 800,202 (299)

A 'double-edged' role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs. [PDF]

open access: yesElife
Notartomaso S   +17 more
europepmc   +1 more source

Cloned Glutamate Receptors

Annual Review of Neuroscience, 1994
The application of molecular cloning technology to the study of the glutamate receptor system has led to an explosion of knowledge about the structure, expression, and function of this most important fast excitatory transmitter system in the mammalian brain.
Michael Hollmann, Stephen Heinemann
exaly   +3 more sources

Glutamate receptors and pain

Seminars in Cell & Developmental Biology, 2006
Pain is an important survival and protection mechanism for animals. However, chronic/persistent pain may be differentiated from normal physiological pain in that it confers no obvious advantage. An accumulating body of pharmacological, electrophysiological, and behavioral evidence is emerging in support of the notion that glutamate receptors play a ...
David, Bleakman   +2 more
openaire   +2 more sources

Structure of Glutamate Receptors

Current Drug Targets, 2007
Glutamate receptors mediate a vast array of processes in plants, animals and bacteria. In particular, the ionotropic glutamate receptors (iGluRs) are the most abundant excitatory neurotransmitter receptors in the mammalian central nervous system. Because these proteins are constructed from distinct folding domains, most of which can be traced to ...
Robert E, Oswald   +3 more
openaire   +2 more sources

Metabotropic glutamate receptors

Cell and Tissue Research, 2006
Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
openaire   +2 more sources

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