Results 241 to 250 of about 314,122 (297)

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors. [PDF]

Front Pharmacol
Valenti O, Rekawek KA, Wieser S, Bulut H, Scholze P, Boehm S.   +5 more
europepmc   +1 more source

Mechanisms of glutamate receptors hypofunction dependent synaptic transmission impairment in the hippocampus of schizophrenia susceptibility gene Opcml-deficient mouse model. [PDF]

Mol Brain
Sun X, Meng H, Lu T, Yue W, Zhang D, Wang L, Li J.   +6 more
europepmc   +1 more source

Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice. [PDF]

eNeuro
Busceti CL, Di Menna L, Castaldi S, D'Errico G, Taddeucci A, Bruno V, Fornai F, Pittaluga A, Battaglia G, Nicoletti F.   +9 more
europepmc   +1 more source

Pharmacological Blockade of Group II Metabotropic Glutamate Receptors Reduces the Incidence of Brain Tumors Induced by Prenatal Exposure to N-ethyl-N-nitrosourea in Rats. [PDF]

Curr Neuropharmacol
Arcella A, Alborghetti M, Traficante A, Oliva MA, Staffieri S, Russo V, Caridi M, Battaglia G.   +7 more
europepmc   +1 more source

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Cloned Glutamate Receptors

Annual Review of Neuroscience, 1994
The application of molecular cloning technology to the study of the glutamate receptor system has led to an explosion of knowledge about the structure, expression, and function of this most important fast excitatory transmitter system in the mammalian brain.
M, Hollmann, S, Heinemann
openaire   +2 more sources

Metabotropic glutamate receptors

Cell and Tissue Research, 2006
Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
openaire   +2 more sources

Glutamate Receptors in Microglia

CNS & Neurological Disorders - Drug Targets, 2013
Expression of functional glutamate receptors (GluR) on glial cells in the developing and mature brain has been recently established. Over the last decade there has been physiological, molecular and biochemical evidence suggesting the presence of GluR on microglia. However, the significance of GluR activation in microglia remains largely unknown.
Madhuvika, Murugan, Eng-Ang, Ling, Charanjit, Kaur   +2 more
openaire   +2 more sources

Glutamate Receptor Gating

Critical Reviews in Neurobiology, 2004
Ionotropic glutamate receptors (iGluRs) mediate the vast majority of fast excitatory synaptic transmissions within the mammalian central nervous system (CNS). As for other ion channel protein families, there has been astounding progress in recent years in elucidating the details of protein structure through the crystallization of at least part of the ...
Kevin, Erreger, Philip E, Chen, David J A, Wyllie, Stephen F, Traynelis   +3 more
openaire   +2 more sources

Glutamate receptors and pain

Seminars in Cell & Developmental Biology, 2006
Pain is an important survival and protection mechanism for animals. However, chronic/persistent pain may be differentiated from normal physiological pain in that it confers no obvious advantage. An accumulating body of pharmacological, electrophysiological, and behavioral evidence is emerging in support of the notion that glutamate receptors play a ...
David, Bleakman, Andrew, Alt, Eric S, Nisenbaum   +2 more
openaire   +2 more sources