Results 91 to 100 of about 65,396 (291)

Detrimental Effects of Paraquat on Astrocytes-Regulating Synaptic Functions

Dose-Response, 2018
Paraquat (PQ) exposure is known as a risk factor for developing neurodegenerative diseases. Astrocytes are implicated and affected in neurodegenerative diseases and brain injuries, so it is suspected that PQ may impose detrimental effects on astrocytes ...
Zheng Li, Jing Zheng, Xiao-Feng Zhang
doaj   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

Advanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee, Dongjo Yoon, Jungha Lee, Duhee Kim, Eunui Kim, Jong‐Hyeok Yoon, Hyuk‐Jun Kwon, Seungjun Chung, Yoonkey Nam, Hongki Kang   +9 more
wiley   +1 more source

Gene Expression and Molecular Characterization of a Xylanase from Chicken Cecum Metagenome

International Journal of Microbiology, 2017
A xylanase gene xynAMG1 with a 1,116-bp open reading frame, encoding an endo-β-1,4-xylanase, was cloned from a chicken cecum metagenome. The translated XynAMG1 protein consisted of 372 amino acids including a putative signal peptide of 23 amino acids ...
Hind AL-Darkazali, Vithaya Meevootisom, Duangnate Isarangkul, Suthep Wiyakrutta   +3 more
doaj   +1 more source

Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine

Frontiers in Behavioral Neuroscience, 2014
The meso-cortico-limbic system, via dopamine release, encodes the rewarding and reinforcing properties of natural rewards. It is also activated in response to abused substances and is believed to support drug-related behaviors.
Sebastien eParnaudeau, Sebastien eParnaudeau, Marie-Louise eDongelmans, Marc eTuriault, Frederic eAmbroggi, Frederic eAmbroggi, Anne-Sophie eDelbes, Celine eCansell, Serge H Luquet, Pier Vincenzo Piazza, Francois eTronche, Jacques eBARIK, Jacques eBARIK   +12 more
doaj   +1 more source

Nanomaterial‐Integrated Fiber Neural Probes for Deep Brain Monitoring and Modulation: Challenges and Opportunities

Advanced Functional Materials, EarlyView.
The article presents nanomaterial‐integrated fiber neural probes as innovative tools for deep brain molecular sensing, neural stimulation, and temperature monitoring. It examines breakthroughs in SERS‐based biomolecule detection, thermoplasmonic activation, and luminescent thermometry, alongside strategies to overcome stability, specificity, and ...
Di Zheng, Yang Li, Muhammad Fayyaz Kashif, Linda Piscopo, Massimo De Vittorio, Ferruccio Pisanello   +5 more
wiley   +1 more source

Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease [PDF]

, 2017
Masanobu Kano, Takaki Watanabe
openalex   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation

Nature Communications
Whether and how regulatory events at the translation stage shape the cellular and metabolic features of thermogenic adipocytes is hardly understood.
Daehwa Youn, Boseon Kim, Dahee Jeong, Ju Yeon Lee, Seha Kim, Dulguun Sumberzul, Rehna Paula Ginting, Min-Woo Lee, Ju Hwan Song, Ye Seul Park, Yumin Kim, Chang-Myung Oh, Mihye Lee, Jun Cho   +13 more
doaj   +1 more source

Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population

Applied Food Research
Monosodium glutamate (MSG), a flavor-enhancing substance, was re-evaluated by the European Food Safety Authority (EFSA) in 2017, which established an acceptable daily intake (ADI) of 0–30 mg/kg bw/day.
Weining Tian, Ling yong, Hongjian Miao, Xingfen Yang, Qinzhi Wei, Sheng Wei, Haixia Sui, Xiao Xiao, Jianwen Li, Huali Wang, Shanyawen Li, Jiongjiong Chang, Tong Ou, Weichunbai Zhang, Yan Song, Zhaoping Liu   +15 more
doaj   +1 more source