Results 111 to 120 of about 226,956 (383)

From acute to chronic pain: tapentadol in the progressive stages of this disease entity [PDF]

open access: yes, 2017
OBJECTIVE: Chronic pain is now recognized as a neural disease, which results from a maladaptive functional and structural transformation process occurring over time. In its chronic phase, pain is not just a symptom but also a disease entity.
Coluzzi, Flaminia   +3 more
core  

Glutamate Receptor Channel Kinetics

open access: yesBiophysical Journal, 1988
Single channel recordings from the locust muscle D-glutamate receptor channel were obtained using glutamate concentrations ranging from 10(-6) to 10(-2) M. Channel kinetics were analyzed to aid in the development of a model for the gating mechanism.
R. L. Ramsey   +3 more
openaire   +3 more sources

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

open access: yesAdvanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer   +8 more
wiley   +1 more source

SPRITE and ASSAM: web servers for side chain 3D-motif searching in protein structures [PDF]

open access: yes, 2012
Similarities in the 3D patterns of amino acid side chains can provide insights into their function despite the absence of any detectable sequence or fold similarities.
Artymiuk   +19 more
core   +4 more sources

Osnovi glutamatergičke neurotransmisije [PDF]

open access: yesVojnosanitetski Pregled, 2004
Milovanović Dragan R.   +1 more
doaj   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao   +4 more
wiley   +1 more source

Regulation of Photosynthetic Light Harvesting Involves Intrathylakoid Lumen pH Sensing by the PsbS Protein*

open access: yesJournal of Biological Chemistry, 2004
The biochemical, biophysical, and physiological properties of the PsbS protein were studied in relation to mutations of two symmetry-related, lumen-exposed glutamate residues, Glu-122 and Glu-226.
Xiao-Ping Li   +6 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Proteolytic Hydrolysis of Rice (Oryza Sativa Basmati) [PDF]

open access: yes, 2001
Protein hydrolysate has been produced a long time ago. It is normally use as animal feed or as a substitute for dietary patient and the protein used is usually obtained from seafood.
Ong, Lisa Gaik Ai
core  

Folates in quinoa (Chenopodium quinoa), amaranth (Amaranthus sp.) and buckwheat (Fagopyrum esculentum): Influence of cooking and malting [PDF]

open access: yes, 2017
Effects of processing on the contents of five folate vitamers in quinoa, amaranth and buckwheat were analysed using a trienzymatic extraction method followed by LC–MS/MS.
Arcot, Jayashree   +8 more
core   +1 more source

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