Results 241 to 250 of about 69,631 (334)

Evaluation of TOCSY mixing for sensitivity-enhancement in solid-state NMR and application of 4D experiments for side-chain assignments of the full-length 30 kDa membrane protein GlpG. [PDF]

J Biomol NMR
Öster C, Chevelkov V, Lange A.
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding. [PDF]

Proc Natl Acad Sci U S A
Wagner BC, Steuer-Lodd K, Geibel C, Stadelmann A, Rapp J, Link H, Schramm T, Boodaghian N, Hsiao A, Nussbaum E, Grenzendorfer HP, Albrecht R, Hartmann MD, Forchhammer K, Selim KA, Hughes CC, Petras D.   +16 more
europepmc   +1 more source

A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light

Anaëlle Dumazer, Roser Borràs‐Tudurí, Iona Truong, Xiaojing Cong, Fanny Malhaire, Xavier Rovira, Xavier Gómez‐Santacana, Laurent Givalois, Guillaume Lebon, Amadeu Llebaria, Cyril Goudet   +10 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Cofactor F₄₂₀ tail length distribution in different environmental samples. [PDF]

Heliyon
Wunderer M, Markt R, Prem EM, Peer N, Mullaymeri A, Wagner AO.   +5 more
europepmc   +1 more source

Diverse Distribution of Glutamate and Glutamine in Tumor Microenvironments of Breast-to-Brain Metastasis: Insights from Biochemical Analysis and Molecular Imaging

Jun Tang, Yutong Zhao, Liangpeng Chen, Yangyang Liu, Hexin Xie, Zehui Wu, Lu Zhang, Di Fan, Xiaoxia Xu, Lin Ai, Qian Liu, Huachen Zhu, Deling Li   +12 more
openalex   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

Rewiring the brain: abused drugs and structural plasticity

Frontiers in Pharmacology, 2015
M Foster eOlive, Justin eGass
doaj   +1 more source