Results 21 to 30 of about 9,046 (297)

A chemical-specific adjustment factor for human interindividual differences in kinetics for glutamates (E620-625)

open access: yes, 2021
Use of a default methodology for establishment of a health-based guidance value (HBGV) resulted in a group acceptable daily intake (ADI) for glutamates (E620-625) below the normal dietary glutamate intake, and also lower than the intake of free glutamate
Nakamura, Hidehiro   +5 more
core   +1 more source

Emerging trends in pharmacological strategies for targeting neuroinflammation in depression [PDF]

open access: yesScripta Medica
The article discusses evolving pharmacological strategies for addressing the neuroinflammation in depression, highlighting its role in major depressive disorder.
Kumari Anshu   +3 more
doaj   +1 more source

Glutamate and Epilepsy [PDF]

open access: yesThe Journal of Nutrition, 2000
Epileptic syndromes have very diverse primary causes, which may be genetic, developmental or acquired. In rodent models, altering glutamate receptor or glutamate transporter expression by knockout or knockdown procedures can induce or suppress epileptic seizures.
openaire   +2 more sources

Production ofD-Glutamate fromL-Glutamate with Glutamate Racemase andL-Glutamate Oxidase [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1999
We studied production of D-glutamate from L-glutamate using a bioreactor consisting of two columns of sequentially connected immobilized glutamate racemase (EC 5.1.1.3, from Bacillus subtilis IFO 3336) and L-glutamate oxidase (EC 1.4.3.11, from Streptomyces sp.
OIKAWA, Tadao   +5 more
openaire   +2 more sources

Vicinal glutamates are better phosphomimetics: Phosphorylation is required for allosteric activation of guanylyl cyclase-A

open access: yesFrontiers in Molecular Neuroscience, 2022
Multisite phosphorylation of guanylyl cyclase (GC)-A, also known as NPR-A or NPR1, is required for receptor activation by natriuretic peptides (NPs) because alanine substitutions for the first four GC-A phosphorylation sites produce an enzyme that cannot
Neil M. Otto, Lincoln R. Potter
doaj   +1 more source

Metabotropic Glutamate Receptors Inhibit Microglial Glutamate Release [PDF]

open access: yesASN Neuro, 2012
Pro-inflammatory stimuli evoke an export of glutamate from microglia that is sufficient to contribute to excitotoxicity in neighbouring neurons. Since microglia also express various glutamate receptors themselves, we were interested in the potential feedback of glutamate on this system. Several agonists of mGluRs (metabotropic glutamate receptors) were
Stephen M McMullan   +3 more
openaire   +3 more sources

Roles of glutamate in brain injuries after subarachnoid hemorrhage [PDF]

open access: yes, 2022
Aneurysmal subarachnoid hemorrhage (SAH) is a stroke type with a high rate of mortality and morbidity. Post-SAH brain injury as a determinant of poor outcome is classified into the following two types: early brain injury (EBI) and delayed cerebral ...
Suzuki, Yume   +7 more
core   +1 more source

QM/MM study of the stereospecific proton exchange of glutathiohydroxyacetone by glyoxalase I

open access: yesResults in Chemistry, 2019
We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (
Sonia Jafari, Ulf Ryde, Mehdi Irani
doaj   +1 more source

Glutamate Receptor [PDF]

open access: yes, 2016
[No abstract]
openaire   +2 more sources

Molecular Cloning and Characterization of SaCLCd, SaCLCf, and SaCLCg, Novel Proteins of the Chloride Channel Family (CLC) from the Halophyte Suaeda altissima (L.) Pall

open access: yesPlants, 2022
Coding sequences of the CLC family genes SaCLCd, SaCLCf, and SaCLCg, the putative orthologs of Arabidopsis thaliana AtCLCd, AtCLCf, and AtCLCg genes, were cloned from the euhalophyte Suaeda altissima (L.) Pall.
Olga I. Nedelyaeva   +3 more
doaj   +1 more source

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