Results 21 to 30 of about 8,454 (258)

QM/MM study of the stereospecific proton exchange of glutathiohydroxyacetone by glyoxalase I

open access: yesResults in Chemistry, 2019
We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (
Sonia Jafari, Ulf Ryde, Mehdi Irani
doaj   +1 more source

Re‐evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives

open access: yesEFSA Journal, 2017
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of glutamic acid–glutamates (E 620–625) when used as food additives.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)   +27 more
doaj   +1 more source

Molecular Cloning and Characterization of SaCLCd, SaCLCf, and SaCLCg, Novel Proteins of the Chloride Channel Family (CLC) from the Halophyte Suaeda altissima (L.) Pall

open access: yesPlants, 2022
Coding sequences of the CLC family genes SaCLCd, SaCLCf, and SaCLCg, the putative orthologs of Arabidopsis thaliana AtCLCd, AtCLCf, and AtCLCg genes, were cloned from the euhalophyte Suaeda altissima (L.) Pall.
Olga I. Nedelyaeva   +3 more
doaj   +1 more source

Glutamate Receptor [PDF]

open access: yes, 2016
[No abstract]
openaire   +2 more sources

Phosphine Catalyzed Michael-Type Additions: The Synthesis of Glutamic Acid Derivatives from Arylidene-α-amino Esters

open access: yesMolecules
The reaction of arylidene-α-amino esters with electrophilic alkenes to yield Michael-type addition compounds is optimized using several phosphines as organocatalysts. The transformation is very complicated due to the generation of several final compounds,
Lesly V. Rodríguez-Flórez   +6 more
doaj   +1 more source

Glutamate-induced Exocytosis of Glutamate from Astrocytes

open access: yesJournal of Biological Chemistry, 2007
Recent studies indicate that astrocytes can play a much more active role in neuronal circuits than previously believed, by releasing neurotransmitters such as glutamate and ATP. Here we report that local application of glutamate or glutamine synthetase inhibitors induces astrocytic release of glutamate, which activates a slowly decaying transient ...
Jun, Xu   +6 more
openaire   +2 more sources

Obesity as a Limiting Factor for Remote Ischemic Postconditioning-Mediated Neuroprotection after Stroke

open access: yesJournal of Obesity & Metabolic Syndrome
Background : Remote ischemic postconditioning (RIPostC) may protect the brain from ischemia/reperfusion (I/R) injury. The association between RIPostC and obesity has not yet been extensively studied.
Klaudia Kotorová   +4 more
doaj   +1 more source

Beyond Sulfate-Free Personal Cleansing Technology

open access: yesCosmetics
There is a strong global demand for sulfate-free personal cleansing products. The objective of sulfate-free personal cleansing technology should not be aimed solely at the absence of “sulfate” wording in the list of ingredients, but on the true benefits ...
Evelyn Su, Stephen Herman
doaj   +1 more source

Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases

open access: yesFrontiers in Molecular Neuroscience, 2022
The natriuretic peptide receptors NPR1 and NPR2, also known as guanylyl cyclase A and guanylyl cyclase B, have critical functions in many signaling pathways, but much remains unknown about their localization and function in vivo. To facilitate studies of
Jeremy R. Egbert   +13 more
doaj   +1 more source

Pharmacotherapy of Schizophrenia: Ploypharmacy Approaches [PDF]

open access: yesActa Medica Iranica, 2010
"nSchizophrenia is a debilitating illness, rating as one of the leading causes of lost years of quality of life. The illness imposes a disproportionate burden on patients and their families, healthcare systems and society. Pharmacological management
Fatemeh Rahiminejad, Shahin Akhondzadeh
doaj   +2 more sources

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