Results 21 to 30 of about 70,807 (343)
A structural and functional model for human bone sialoprotein [PDF]
Human bone sialoprotein (BSP) is an essential component of the extracellular matrix of bone. It is thought to be the primary nucleator of hydroxyapatite crystallization, and is known to bind to hydroxyapatite, collagen, and cells.
Durrant, Marcus, Vincent, Kevin
core +1 more source
Microtubule-severing enzymes: From cellular functions to molecular mechanism. [PDF]
Microtubule-severing enzymes generate internal breaks in microtubules. They are conserved in eukaryotes from ciliates to mammals, and their function is important in diverse cellular processes ranging from cilia biogenesis to cell division, phototropism ...
Ahmad +130 more
core +2 more sources
Liability of a Surgeon for the Extension of an Authorized Operation [PDF]
Polyunsaturated fatty acids modulate the voltage dependence of several voltage-gated ion channels, thereby being potent modifiers of cellular excitability.
Billman +43 more
core +2 more sources
Glutamate-induced Exocytosis of Glutamate from Astrocytes
Recent studies indicate that astrocytes can play a much more active role in neuronal circuits than previously believed, by releasing neurotransmitters such as glutamate and ATP. Here we report that local application of glutamate or glutamine synthetase inhibitors induces astrocytic release of glutamate, which activates a slowly decaying transient ...
Jun, Xu +6 more
openaire +2 more sources
QM/MM study of the stereospecific proton exchange of glutathiohydroxyacetone by glyoxalase I
We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (
Sonia Jafari, Ulf Ryde, Mehdi Irani
doaj +1 more source
Glutamate transporter control of ambient glutamate levels
Accurate knowledge of the ambient extracellular glutamate concentration in brain is required for understanding its potential impacts on tonic and phasic receptor signaling. Estimates of ambient glutamate based on microdialysis measurements are generally in the range of ∼2-10μM, approximately 100-fold higher than estimates based on electrophysiological ...
Sun, Weinan +3 more
openaire +2 more sources
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of glutamic acid–glutamates (E 620–625) when used as food additives.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) +27 more
doaj +1 more source
Coding sequences of the CLC family genes SaCLCd, SaCLCf, and SaCLCg, the putative orthologs of Arabidopsis thaliana AtCLCd, AtCLCf, and AtCLCg genes, were cloned from the euhalophyte Suaeda altissima (L.) Pall.
Olga I. Nedelyaeva +3 more
doaj +1 more source
The reaction of arylidene-α-amino esters with electrophilic alkenes to yield Michael-type addition compounds is optimized using several phosphines as organocatalysts. The transformation is very complicated due to the generation of several final compounds,
Lesly V. Rodríguez-Flórez +6 more
doaj +1 more source

