Results 31 to 40 of about 9,046 (297)

Glutamate-induced Exocytosis of Glutamate from Astrocytes

open access: yesJournal of Biological Chemistry, 2007
Recent studies indicate that astrocytes can play a much more active role in neuronal circuits than previously believed, by releasing neurotransmitters such as glutamate and ATP. Here we report that local application of glutamate or glutamine synthetase inhibitors induces astrocytic release of glutamate, which activates a slowly decaying transient ...
Jun, Xu   +6 more
openaire   +2 more sources

Phosphine Catalyzed Michael-Type Additions: The Synthesis of Glutamic Acid Derivatives from Arylidene-α-amino Esters

open access: yesMolecules
The reaction of arylidene-α-amino esters with electrophilic alkenes to yield Michael-type addition compounds is optimized using several phosphines as organocatalysts. The transformation is very complicated due to the generation of several final compounds,
Lesly V. Rodríguez-Flórez   +6 more
doaj   +1 more source

Obesity as a Limiting Factor for Remote Ischemic Postconditioning-Mediated Neuroprotection after Stroke

open access: yesJournal of Obesity & Metabolic Syndrome
Background : Remote ischemic postconditioning (RIPostC) may protect the brain from ischemia/reperfusion (I/R) injury. The association between RIPostC and obesity has not yet been extensively studied.
Klaudia Kotorová   +4 more
doaj   +1 more source

Caged Glutamates with π‑Extended 1,2-Dihydronaphthalene Chromophore: Design, Synthesis, Two-Photon Absorption Property, and Photochemical Reactivity

open access: yes, 2016
Caging and photochemical uncaging of the excitatory neurotransmitter l-glutamate (glu) offers a potentially valuable tool for understanding the mechanisms of neuronal processes.
Srikanth Boinapally (1754347)   +8 more
core   +1 more source

Beyond Sulfate-Free Personal Cleansing Technology

open access: yesCosmetics
There is a strong global demand for sulfate-free personal cleansing products. The objective of sulfate-free personal cleansing technology should not be aimed solely at the absence of “sulfate” wording in the list of ingredients, but on the true benefits ...
Evelyn Su, Stephen Herman
doaj   +1 more source

Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases

open access: yesFrontiers in Molecular Neuroscience, 2022
The natriuretic peptide receptors NPR1 and NPR2, also known as guanylyl cyclase A and guanylyl cyclase B, have critical functions in many signaling pathways, but much remains unknown about their localization and function in vivo. To facilitate studies of
Jeremy R. Egbert   +13 more
doaj   +1 more source

Caged Glutamates with π-Extended 1,2-Dihydronaphthalene Chromophore: Design, Synthesis, Two-Photon Absorption Property, and Photochemical Reactivity

open access: yes, 2014
This work was granted access to the HPC resources of CINES and of IDRIS under the allocations 2013-[x2013080649] made by GENCI (Grand Equipement National de Calcul Intensif).International audienceCaging and photochemical uncaging of the excitatory ...
Xue, Bing   +17 more
core   +1 more source

Pharmacotherapy of Schizophrenia: Ploypharmacy Approaches [PDF]

open access: yesActa Medica Iranica, 2010
"nSchizophrenia is a debilitating illness, rating as one of the leading causes of lost years of quality of life. The illness imposes a disproportionate burden on patients and their families, healthcare systems and society. Pharmacological management
Fatemeh Rahiminejad, Shahin Akhondzadeh
doaj   +2 more sources

Homopolypeptides derived from substituted β-Benzyl-L-aspartates and γ-Benzyl-L-glutamates

open access: yes, 1966
Homopolypeptides have been obtained by polymerization of the N-carboxy anhydrides of various substituted β-benzyl-L-aspartates and γ-benzyl-L- glutamates.
R Ledger, FHC Stewart
core   +1 more source

Expression and purification of recombinant vesicular glutamate transporter VGLUT1 using PC12 cells and High Five insect cells

open access: yesBiological Procedures Online, 2004
In synaptic vesicles, the estimated concentration of the excitatory amino acid glutamate is 100-150 mM. It was recently discovered that VGLUT1, previously characterized as an inorganic phosphate transporter (BNPI) with 9-11 predicted transmembrane ...
Andersen Søren S.L.
doaj   +1 more source

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