Results 61 to 70 of about 9,046 (297)

Étude par absorption dipolaire de la transition hélice-chaîne de plusieurs poly-γ-glutamates de benzyle stéréoisomères en solvant binaire

, 2017
On donne les courbes de variation de la constante diélectrique lors de la transition hélice-chaîne de plusieurs poly-γ-glutamates de benzyle qui diffèrent par l’ordre dans lequel se succèdent les motifs D et L.
Claude Dufour, Gérard Spach, Eve Marchal   +2 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Synthesis and photochemical reactivity of caged glutamates with a π-​extended coumarin chromophore as a photolabile protecting group

, 2013
International audience'Caging' and 'uncaging' bioactive substrates are key techniques in studying a wide variety of biological processes. In the present study, two-types of novel caged glutamates with a two-photon absorption (TPA) core, that is, π ...
Boinapally, Srikanth, Abe, Manabu, Sakamoto, Yuya, Katan, Claudine   +3 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Synthesis, Characterization, Liquid Crystals and Crosslinking of Poly(gamma-Alkyl-Alpha,L-Glutamates).

, 1995
As most polypeptides, poly($\gamma$-alkyl-$\alpha$,L-glutamates) exhibit the ability to exist in well defined chain conformations of extensive order such as the $\alpha$-helix.
Nakamatsu, Javier
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Two conserved glutamates in the bacterial nitric oxide reductase are essential for activity but not assembley of the enzyme

, 2001
oai:ueaeprints.uea.ac.uk:1The bacterial nitric oxide reductase (NOR) is a divergent member of the family of respiratory heme-copper oxidases. It differs from other family members in that it contains an FeB–heme-Fe dinuclear catalytic center rather than a
Watmough, N.J., Spiro, S., Butland, G., Richardson, D.J.   +3 more
core   +1 more source

Glutamate neurocircuitry: theoretical underpinnings in schizophrenia

Frontiers in Pharmacology, 2012
The Dopamine Hypothesis of Schizophrenia is actively being challenged by the NMDA Receptor Hypofunctioning Hypothesis of Schizophrenia. The latter hypothesis may actually be the starting point in neuronal pathways that ultimately modifies dopamine ...
Thomas L Schwartz, Shilpa eSachdeva, Stephen M Stahl, Stephen M Stahl   +3 more
doaj   +1 more source

Glutamate signaling in bone

Frontiers in Endocrinology, 2012
Mechanical loading plays a key role in the physiology of bone, allowing bone to functionally adapt to its environment, however characterization of the signaling events linking load to bone formation is incomplete. A screen for genes associated with mechanical load-induced bone formation identified the glutamate transporter GLAST, implicating the ...
Brakspear, Karen S., Mason, Deborah J.
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source