Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
What does the mediodorsal thalamus do?
Frontiers in Systems Neuroscience, 2013 Dense amnesia can result from damage to the medial diencephalon in humans and in animals. In humans this damage is diffuse and can include the mediodorsal nuclei of the thalamus.
Anna S Mitchell, Subhojit eChakraborty
doaj +1 more source
Glutamate Uptake Is Not Impaired by Hypoxia in a Culture Model of Human Fetal Neural Stem Cell-Derived Astrocytes [PDF]
, 2022 Vadanya Shrivastava +11 more
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Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis
Arthritis Care &Research, EarlyView.Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher +2 more
wiley +1 more source
Sirtuin 4 Inhibits Prostate Cancer Progression and Metastasis by Modulating p21 Nuclear Translocation and Glutamate Dehydrogenase 1 ADP-Ribosylation [PDF]
, 2022 Liang Mao +8 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Osnovi glutamatergičke neurotransmisije [PDF]
Vojnosanitetski Pregled, 2004 Milovanović Dragan R. +1 more
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Oxoglutarate dehydrogenase complex controls glutamate-mediated neuronal death
, 2023 Adelheid Weidinger +19 more
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Genetic Disruption of System xc-Mediated Glutamate Release from Astrocytes Increases Negative-Outcome Behaviors While Preserving Basic Brain Function in Rat [PDF]
, 2023 Evan Hess +12 more
openalex +1 more source
Advanced Functional Materials, EarlyView.This work presents a high‐entropy doped NaV0.95 (Fe, Mn, Ni, Al, Ca)0.05PO4F cathode, which enables the whole utilization of Na ions, enhances the reaction kinetics without carbon coating, and realizes a solid‐solution reaction mechanism with a single‐crystal structure.
Yingkai Hua +10 more
wiley +1 more source