Results 71 to 80 of about 66,132 (287)
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Osnovi glutamatergičke neurotransmisije [PDF]
Milovanović Dragan R. +1 more
doaj +1 more source
From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini +2 more
wiley +1 more source
Glutamate-Induced Hyperglycemia.
SummaryPlasma glucose rose linearly with increasing amounts of glutamate up to a maximal dose of 0.2 mmoles/100 g body weight. The glutamate effect could not be explained by stoichiometric conversion of glutamate to glucose. Glutamate produced hyper-glycemia after 14-hour fast, at which time glucagon had no effect on glucose concentration ...
R, Marcus, G, Reaven
openaire +2 more sources
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah +5 more
wiley +1 more source
Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site
Background Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases.
Misquitta Stephanie A +3 more
doaj +1 more source
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
Background: Considering the effect of statins on the regulation of dopamine neurotransmitters and glutamates and importance of the treatment of obsessive-compulsive disorder (OCD) due to its relatively high prevalence and disability of available drugs in
Shahla Akouchekian +4 more
doaj +1 more source
Do's and Don'ts When Visiting Circularly Polarized Luminescence
This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Detrimental Effects of Paraquat on Astrocytes-Regulating Synaptic Functions
Paraquat (PQ) exposure is known as a risk factor for developing neurodegenerative diseases. Astrocytes are implicated and affected in neurodegenerative diseases and brain injuries, so it is suspected that PQ may impose detrimental effects on astrocytes ...
Zheng Li, Jing Zheng, Xiao-Feng Zhang
doaj +1 more source

