Results 71 to 80 of about 221,194 (241)

Hyperactivation in the habenula as a link between depression and sleep disturbance

open access: yesFrontiers in Human Neuroscience, 2013
Depression occurs frequently with sleep disturbance such as insomnia. Sleep in depression is associated with disinhibition of the rapid eye movement (REM) sleep.
Hidenori eAizawa   +3 more
doaj   +1 more source

Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

open access: yesBMC Biology, 2004
Background Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases.
Misquitta Stephanie A   +3 more
doaj   +1 more source

Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation

open access: yesNature Communications
Whether and how regulatory events at the translation stage shape the cellular and metabolic features of thermogenic adipocytes is hardly understood.
Daehwa Youn   +13 more
doaj   +1 more source

The role of glutamate in dementia

open access: yes, 1998
Glutamate is an excitatory neurotransmitter, but may also act as an endogenous neurotoxin. There is good evidence for an involvement of the glutamatergic system in the pathophysiology of dementia. The glutamatergic transmission machinery is quite complex and provides a gallery of possible drug targets.
Kornhuber, J.   +4 more
openaire   +4 more sources

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