Results 11 to 20 of about 42,820 (244)

Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia

Frontiers in Neurology, 2023
The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case
Caio César Diniz Disserol, Caio César Diniz Disserol, Dora Pedroso Kowacs, Samir Kanaan Nabhan, Hélio Afonso Ghizoni Teive, Pedro André Kowacs, Pedro André Kowacs   +6 more
doaj   +1 more source

Glutamic Acid Decarboxylase Concentration Changes in Response to Stress and Altered Availability of Glutamic Acid in Rabbit (Oryctolagus cuniculus) Brain Limbic Structures

Animals, 2021
Glutamic acid decarboxylase (GAD) is an enzyme that catalyses the formation of γ-aminobutyric acid (GABA), the most important inhibitory neurotransmitter, from glutamic acid (Glu), which is considered the most important excitatory transmitter in the ...
Izabela Szpręgiel, Danuta Wrońska, Michał Kmiecik, Sylwia Pałka, Bogdan F. Kania   +4 more
doaj   +1 more source

Progressive Encephalomyelitis with Rigidity and Myoclonus Treated with Rituximab: Case Report and Review of the Literature

Brown Journal of Hospital Medicine, 2022
A woman in her 50s presented with hyper-religiosity, auditory hallucinations, episodes of staring associated with unresponsiveness and stiffening of her entire body. A broad workup excluded autoimmune encephalitis, sarcoidosis, and prion disease. She was
Carlin Chuck, Karl Herman, Sleiman El Jamal   +2 more
doaj   +1 more source

Glutamic Acid Decarboxylase in Legumes [PDF]

Nature, 1956
Since the pioneer researches of Okuniki1,2 and Schales and his associates3–5 on glutamic acid decarboxylase, rather scanty data have been made available on amino-acid decarboxylases of plants. Most of the work deals with glutamic acid decarboxylase of higher plants; so it was thought of interest to study the enzyme system in the case of dry seeds of ...
L, KULKARNI, K, SOHONIE
openaire   +2 more sources

Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. [PDF]

, 2020
Developmental and epileptic encephalopathies are a heterogeneous group of early-onset epilepsy syndromes dramatically impairing neurodevelopment. Modern genomic technologies have revealed a number of monogenic origins and opened the door to therapeutic ...
Alix, E, Alkaya, DU, Ashrafzadeh, F, Becker, F, Bilguvar, K, Chatron, N, de Bellescize, J, EuroEpinomics-RES consortium AR working group, Gunes, N, Hardies, K, Hussien, H, Karimiani, EG, Kok, F, Labalme, A, Lerche, H, Lesca, G, Maroofian, R, May, P, Morsy, H, Moslemi, A-R, Nabil, A, Najafi, M, Omar, T, Poulat, A-L, Ramos, L, Roselli, S, Sanlaville, D, Schmidts, M, Tajsharghi, H, Tuysuz, B, Weckhuysen, S   +30 more
core   +2 more sources

Atypical parkinsonism and intrathecal anti-glutamic acid decarboxylase antibodies – an unusual association: a case report

Journal of Medical Case Reports, 2020
Background Immunological causes of parkinsonism are very rare and usually characterized by early presentation, poor response to levodopa, and additional clinical features.
Giovanni Stefanoni, Anna Formenti, Lucio Tremolizzo, Andrea Stabile, Ildebrando Appollonio, Carlo Ferrarese   +5 more
doaj   +1 more source

Ataxia associated with anti-glutamic acid decarboxylase antibodies

Неврология, нейропсихиатрия, психосоматика, 2020
Anti-glutamic acid decarboxylase (GAD) antibody-associated ataxia is a rarely diagnosed but potentially curable disease associated with autoimmune damage to and death of Purkinje cells in the cerebellar cortex.
E. P. Nuzhnyi, M. Yu. Krasnov, D. R. Akhmadullina, A. A. Abramova, E. Yu. Fedotova, S. N. Illarioshkin   +5 more
doaj   +1 more source

The evaluation of pancreas β-cell autoantibodies in non-diabetic COVID-19 patients

Archives of Endocrinology and Metabolism, 2022
Objective: This study aims to evaluate potential pancreas endocrine damage due to SARS-CoV-2 by measuring β-cell autoantibodies in COVID-19 patients. Subjects and methods: Between June and July 2020, 95 inpatients with a positive COVID-19 test result ...
Sanem Kayhan, Sema Hepsen, Hatice Kozan Kalkisim, Ibrahim Nahit Sendur, Fatma Aybala Altay, Ali Yalcindag   +5 more
doaj   +1 more source

γ-Aminobutyric acid found in fermented foods and beverages: current trends

Heliyon, 2020
γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH).
Novia R.M. Sahab, Edy Subroto, Roostita L. Balia, Gemilang L. Utama   +3 more
doaj   +1 more source

A unique profile of insulin antibody titer in islet‐transplanted patients

Journal of Diabetes Investigation, 2022
Insulin antibodies (IAs) can cause glycemic variability. Islet transplantation (ITx) is a treatment for insulin‐deficient diabetes that aims to establish on‐target glycemic control in the absence of hypoglycemia.
Yamato Keidai, Junji Fujikura, Toshihiro Nakamura, Takayuki Anazawa, Ryo Ito, Masahito Ogura, Etsuro Hatano, Nobuya Inagaki   +7 more
doaj   +1 more source