Results 161 to 170 of about 24,633 (278)

Identification of Inhibitors of Phosphate-activated Glutaminase for the Pharmacotherapy of Schizophrenia

, 2022
In the brain, phosphate-activated glutaminase catalyzes the recycling of glutamine back to glutamate for excitatory neurotransmission. In mice, genetic knockdown of phosphate-activated glutaminase has been shown to confer resilience to schizophrenia-like
Mihali, Andra, Rayport, Stephen, Katz, Francine, Sorrento, Cristina, MacDonald, Joanne, Subramani, Shreya   +5 more
core  

Role of dorsal root ganglion glutaminase in acute and chronic inflammatory pain

, 2013
Scope and methods of the study.The purpose of this study was to provide further evidence to support the concept that dorsal root ganglion (DRG) glutaminase, the synthetic enzyme for the neurotransmitter glutamate, is a potential target for analgesic ...
Zhang, Zijia
core  

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

An Overview of Asparaginase Enzyme Features: An Anticancer Enzyme with High Potency

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introduction: One of the important findings in the pharmaceutical and medical industry is the use of the asparaginazase enzyme as an anticancer drug. The asparaginase enzyme, hydrolyzing the amino acid of asparagine, reduces this amino acid in the blood ...
Gholam Hossein Ebrahimipour, Mahtab Ghorban Movahed   +1 more
doaj  

Safety evaluation of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT

EFSA Journal
The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT by Amano Enzyme Inc.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Magdalena Andryszkiewicz, Daniele Cavanna, Yi Liu, Simone Lunardi, Elsa Nielsen, Karin Norby, Giulio diPiazza, Yrjö Roos, Andrew Chesson   +26 more
doaj   +1 more source

Optimization of culture conditions for production of L-glutaminase enzyme from Klebsiella pneumoniae

The main objective of this study was to investigate the production and activity of glutaminase by some clinical bacterial species. Two marine specimens, saltwater and sediment gathered from the Red Sea coast of Hurghada, Egypt, yielded 100 marine ...
Ibrahim, Asmaa E.M., Elariny, Eman. Y.T., Abdel-Hafez, Lina J.M.   +2 more
core  

Role of Nitrogen Source for L-Glutaminase Production from Fungal Strain using through Submerged Fermentation

L-glutaminase has attracted much attention due its wide range of applications in several fields. The L-glutaminase widely used in pharmaceutical and food industries. L-glutaminase is generally regarded as a key enzyme that controls the delicious taste of
Krishna, Manjunath Basappa Channi, Harish Kumar T. S, Parimala B   +3 more
core   +1 more source

LIVER GLUTAMINASES

Journal of Biological Chemistry, 1949
openaire   +2 more sources

Structure and enzymology of glutaminase S482C and H461L variants associated with excess brain glutamate and neurological disease. [PDF]

J Biol Chem
Crane CS, McIssac TK, Milano SK, Cerione RA, Ulrich SM.   +4 more
europepmc   +1 more source

Safety evaluation of the food enzyme glutaminase from the genetically modified <i>Bacillus subtilis</i> strain Glu3-3. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Aguilera J, Andryszkiewicz M, Cavanna D, Liu Y.   +16 more
europepmc   +1 more source