Results 121 to 130 of about 750,830 (294)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism

Foods
Terpinen-4-ol (T-4-O) is an important component of tea tree oil and has anti-inflammatory effects. Currently, there are very few studies on the mechanisms by which T-4-O improves lipopolysaccharide (LPS)-induced macrophage inflammation.
Yanhui Liu, Xin Tang, Huazhen Zhang, Linyan Zheng, Ping Lai, Chang Guo, Jingfan Ma, Hongbo Chen, Longxin Qiu   +8 more
doaj   +1 more source

Glutamine as a Growth Factor for Certain Strains of Neisseria Gonorrhoeae [PDF]

, 1943
C. E. Lankford, Esmond E. Snell
openalex   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

High glutamine increases stroke risk by inducing the endothelial‐to‐mesenchymal transition in moyamoya disease

MedComm
At present, there is limited research on the mechanisms underlying moyamoya disease (MMD). Herein, we aimed to determine the role of glutamine in MMD pathogenesis, and 360 adult patients were prospectively enrolled.
Qiheng He, Junsheng Li, Chuming Tao, Chaofan Zeng, Chenglong Liu, Zhiyao Zheng, Siqi Mou, Wei Liu, Bojian Zhang, Xiaofan Yu, Yuanren Zhai, Jia Wang, Qian Zhang, Yan Zhang, Dong Zhang, Jizong Zhao, Peicong Ge   +16 more
doaj   +1 more source

Note on the Preparation of Phenyl Thiohydantoins from Glutamine, S-Carboxymethyl Cysteine, and Cysteic Acid. [PDF]

, 1956
Pehr Edman, K Lauber, Udda Lundqvist, Einar Stenhagen, B. Thorell   +4 more
openalex   +1 more source

Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo

Advanced Functional Materials, EarlyView.
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić, Albert Espona‐Noguera, Angela Privat Maldonado, Patrik Matušů, Francesco Tampieri, Maria‐Pau Ginebra, Abraham Lin, Evelien Smits, Annemie Bogaerts, Cristina Canal   +9 more
wiley   +1 more source

DETERMINATION OF AMMONIA, GLUTAMINE, AND ASPARAGINE AMIDE NITROGEN IN PLANT JUICE [PDF]

, 1940
Frank S. Schlenker
openalex   +1 more source

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

Advanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma, Om Shanker Tiwari, Vijay Kumar Patel, Ruchi Shukla, Ehud Gazit, Pandeeswar Makam   +5 more
wiley   +1 more source

Studies on the glutamine and glutamic acid content of the rat liver during insulin hypoglycaemia [PDF]

, 1950
R. M. C. Dawson, R. B. Williams
openalex   +1 more source