Results 131 to 140 of about 538,260 (299)

Cell‐Free DNA as a Biomarker of Cell Death and Treatment Response for On‐Chip Three‐Dimensional Tumor Models

Advanced Healthcare Materials, EarlyView.
This study presents quantifying cell‐free DNA (cfDNA) as a non‐disruptive and rapidly quantifiable method for assessing cell death for on‐chip 3D sarcoma tumor models. On‐chip cfDNA release reflects tumor burden, extent of cell death, and survival of in vitro and ex vivo 3D models, providing valuable insight into the temporal response of tumor models ...
Maryam Ziaee, Julie Lafontaine, Badr Id Said, Kousha Kamal, Kim Tsoi, Francis Rodier, Thomas Gervais, Philip Wong   +7 more
wiley   +1 more source

Glutamine

Journal of British Surgery, 1999
S D, Heys, F, Ashkanani
openaire   +2 more sources

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Absence of glutamine isotopic steady state: implications for the assessment of whole-body glutamine production rate.

, 1998
Department of Surgery, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands. 1.During infusion of [5-15N]glutamine in patients with gastrointestinal cancer we unexpectedly observed a gradual decrease in time of the appearance ...
von Meyenfeldt, M.F., van Acker, B.A.C., Matthews, D.E., Wagenmakers, A.J.M., Soeters, P.B., van Kreel, B.K., Halliday, D., Deutz, N.E.P., Hulsewé, K.W.E.   +8 more
core   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

Advanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg, Franco A. Laimo, Stefano Ippolito, Prastuti Upadhyay, Spencer R. Averbeck, Dimitris Boufidis, Charles‐Antoine Assenmacher, Dayo O. Adewole, Sai Panigrahy, Bita Soltan Mohammadlou, Lucy Plant, Yuan Zhang, Andrew G. Richardson, Yury Gogotsi, D. Kacy Cullen, Flavia Vitale   +15 more
wiley   +1 more source

Glutamine Metabolism in Brain Tumors

, 2019
Altered metabolism is a hallmark of cancer cells. Tumor cells rewire their metabolism to support their uncontrolled proliferation by taking up nutrients from the microenvironment.
Siva Kumar Natarajan, Sriram Venneti
core   +1 more source

Graphene Layers as Functional Biomaterials. From Fabrication and Characterization to Biological Applications

Advanced Materials Interfaces, EarlyView.
Graphene layers are fabricated on Cu foil and transferred onto glass substrates to form double‐ and multi‐layer G‐glass. Raman spectroscopy confirms structural integrity, while SEM and fluorescence microscopy reveal favorable adhesion and spreading of L‐929 fibroblast cells.
Mariana Mihaela Apostol, Issam Boukhoubza, Daniela Oprea, Iulia Corina Ciobotaru, Catalin Negrila, Ionut Enculescu, Ecaterina Andronescu, Teodor Adrian Enache, Elena Matei   +8 more
wiley   +1 more source

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

Advanced Materials Interfaces, EarlyView.
Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi, Aniruddh Murali, Ellen Juel Pørtner, Adam Cohen Simonsen, Francesca Serra   +4 more
wiley   +1 more source

Congenital Glutamine Deficiency with Glutamine Synthetase Mutations [PDF]

New England Journal of Medicine, 2006
Rose, Christopher, Jalan, Rajiv
openaire   +2 more sources