Results 201 to 210 of about 178,237 (260)

Identification of Histone Deacetylase Inhibitor Targeting Type I Interferon and B Cell Abnormalities in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

DIO3 depletion attenuates ovarian cancer growth via reduced glycolysis and alterations in glutamine metabolism. [PDF]

Mol Metab
Moskovich D, Beilinson D, Rosemarin A, Cohen A, Fabian I, Lifschytz T, Lerer B, Mugesh G, Gottfried M, Ashur-Fabian O.   +9 more
europepmc   +1 more source

Expression of concern 'Influence of glutamine metabolism on diabetes Development: A scientometric review'. [PDF]

Heliyon
europepmc   +1 more source

Developing a prognostic model of glutamine metabolism-related genes associated with clinical features and immune status in melanoma. [PDF]

Front Oncol
Hu H, Yang J, Miao J, Li C, Wang C, Ran F, Zou J, Zhang Y, Zhao L, Zhao W, Ai C.   +10 more
europepmc   +1 more source

Beyond the tumor: Enhancing pancreatic cancer therapy through glutamine metabolism and innovative drug delivery. [PDF]

J Cell Commun Signal
Su M, Qin H, Shen J, An H, Cao Y.
europepmc   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis. [PDF]

Adv Sci (Weinh)
Chen M, Meng X, Zhu Y, Wang D, Wang M, Wang Z, Tian X, Zhang J, Yue Z, Yang Z, Wang R.   +10 more
europepmc   +1 more source

Association between folate and glutamine metabolism and prognosis of kidney cancer. [PDF]

Front Nutr
Qin J, Ouyang C, Zhuang X.
europepmc   +1 more source

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Lung Glutamine Metabolism

Journal of Parenteral and Enteral Nutrition, 1990
The role of the lungs in maintaining amino acid homeostasis has only recently been studied. The data suggest that the lungs play a key role in glutamine flow in both normal and catabolic states. Further studies are necessary to clarify the regulation of lung glutamine at the whole organ and cellular level.
W W, Souba, K, Herskowitz, D A, Plumley
openaire   +2 more sources

Gut Glutamine Metabolism

Journal of Parenteral and Enteral Nutrition, 1990
The gut plays a key role in interorgan glutamine metabolism in normal and catabolic states. During critical illness, the gut responds to prevailing metabolic pressures that may result in a temporary "reset" in interorgan glutamine flow. As the body recovers from the disease process, the alterations in gut glutamine metabolism revert to normal, which ...
W W, Souba, K, Herskowitz, R M, Salloum, M K, Chen, T R, Austgen   +4 more
openaire   +2 more sources

Hepatic glutamine metabolism

Nutrition, 2002
Expression of high activities of both glutamine synthetase and glutaminase allows the liver to play a major role in the regulation of glutamine homeostasis. The liver shows net glutamine output in metabolic acidosis, in prolonged starvation and animals bearing tumors, net glutamine uptake in the postabsorptive state, on consuming high protein diets ...
Malcolm, Watford, Vinolia, Chellaraj, Afshan, Ismat, Petrice, Brown, Priya, Raman   +4 more
openaire   +3 more sources