Results 111 to 120 of about 78,410 (212)

Comparative Analysis of Lysophosphatidic Acid Levels in Fibromyalgia and Other Painful Conditions in Female Patients

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Previous work found a decrease in lysophosphatidylcholines (LPCs) in fibromyalgia (FM) serum, prompting the hypothesis that this decrease could be due to increased conversion of LPC to lysophosphatidic acid (LPA) through autotaxin (ATX). LPA has pronociceptive functions, and increased LPA levels could modulate FM pain.
Joana Menezes   +10 more
wiley   +1 more source

Temporal Profiling of Male Cortical Astrocyte Transcription Predicts Molecular Shifts From Early Development to Aging

open access: yesGlia, Volume 73, Issue 7, Page 1349-1364, July 2025.
Main Points Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain.
Xiaoran Wei   +2 more
wiley   +1 more source

Delineation of monocytic and early‐stage myeloid‐derived suppressor cells in the peripheral blood of patients with hepatocarcinoma

open access: yesInternational Journal of Cancer, Volume 156, Issue 12, Page 2416-2428, 15 June 2025.
What's new? In hepatocellular carcinoma, expanded myeloid‐derived suppressor cells (MDSC) relate to aggressiveness and poor prognosis. A global analysis of the different MDSC subsets in hepatocellular carcinoma is, however, missing. In this study, all three subsets of M‐MDSC, PMN‐MDSC, and eMDSC, together with arginase 1 activity, were significantly ...
Marta Chivite‐Lacaba   +13 more
wiley   +1 more source

Glutamine synthetase-negative hepatocellular carcinoma has better prognosis and response to sorafenib treatment after hepatectomy. [PDF]

open access: yesChin Med J (Engl), 2023
Shao M   +13 more
europepmc   +1 more source

Shifting Patterns of Nitrogen Excretion and Amino Acid Catabolism Capacity during the Life Cycle of the Sea Lamprey (\u3cem\u3ePetromyzon mariunus\u3c/em\u3e) [PDF]

open access: yes, 2006
The jawless fish, the sea lamprey (Petromyzon marinus), spends part of its life as a burrow-dwelling, suspension-feeding larva (ammocoete) before undergoing a metamorphosis into a free swimming, parasitic juvenile that feeds on the blood of fishes.
Claude, Jaime F.   +6 more
core   +1 more source

Sigma Factors as Potential Targets to Enhance Recombinant Protein Expression

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 6, Page 1598-1607, June 2025.
ABSTRACT The transcriptional factors control the expression of many genes and represent an important layer of complexity in cell factories. However, the effect of individual sigma factor deletions from a biomanufacturing perspective has not been addressed. In this contribution, growth, green fluorescence protein (GFP) expression, and oxygen consumption
Laura Pohlen   +6 more
wiley   +1 more source

Heliorhodopsin binds and regulates glutamine synthetase activity. [PDF]

open access: yesPLoS Biol, 2022
Cho SG   +5 more
europepmc   +1 more source

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