Effect of diabetes on glutamine synthetase expression in rat skeletal muscles [PDF]
, 1990 The regulation of glutamine synthetase expression in muscles from normal and diabetic (streptozotocin-treated) rats was studied. Muscle and body weights were markedly reduced in diabetic animals.
C. Banner, B. Feng, S. R. Max
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Metabolic brain disease, 2013 At high concentrations, the glutamine synthetase inhibitor L-methionine-S,R-sulfoximine (MSO) is a convulsant, especially in dogs. Nevertheless, sub-convulsive doses of MSO are neuroprotective in rodent models of hyperammonemia, acute liver disease, and ...
T. Jeitner, Arthur James Cooper
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Cerebellar glutamine synthetase in children after hypoxia or ischemia. [PDF]
, 1991 Glutamate has been implicated in the pathophysiology of acute hypoxic-ischemic encephalopathy. Glutamine synthetase is an enzyme found in astrocytes that converts glutamate to its nontoxic analogue, glutamine.
M Ahdab-Barmada, N F Schor, D N Dao
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Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation [PDF]
, 2010 During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
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Glutamine synthetase from the plant fraction of Phaseolus root nodules Purification of the mRNA and in vitro synthesis of the enzyme [PDF]
, 1983 Antiserum raised to glutamine synthetase (GS) from the plant fraction of Phaseolus vulgaris root nodules was used to immunoprecipitate in vitro translation products of nodule and root poly(A)+ RNA.
Cullimore, Julie V. +5 more
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Influence of solutes on the inactivation of glutamine synthetase by endopeptidases [PDF]
, 1987 Glutamine synthetase (GS) extracted from young wheat leaves (low endopeptidase activity) is relatively stable at pH 7.5 and 30°C, but is rapidly inactivated when extract from senescing wheat leaves (high endopeptidase activity), purified papain or ...
Fröhlich, V, Feller, Urs
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Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina [PDF]
, 2005 PURPOSE: Kinetic studies of photoreceptor cell death in the retinal degeneration (rd1) mouse model suggest that photoreceptor degeneration could result from cumulative damage.
Neveux, N +5 more
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Congenital Glutamine Deficiency with Glutamine Synthetase Mutations [PDF]
New England Journal of Medicine, 2006 Rose, Christopher, Jalan, Rajiv
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Role of glutamine synthetase in citric acid fermentation byAspergillus niger [PDF]
, 1985 The activity of glutamine synthetase fromAspergillus niger was significantly lowered under conditions of citric acid fermentation. The intracellular pH of the organism as determined by bromophenol blue dye distribution and fluorescein diacetate uptake ...
Appaji Rao, N +2 more
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Glutamine synthesis and synthetase in guinea pig kidney [PDF]
, 1983 It is now generally believed that kidneys of many species increase ammonia excretion (through the action of glutaminases) in the urine, in response to an acid challenge, and that the physiological significance of such enhanced ammoniagenesis is to ...
Quarcoo, Ezekiel Tawia
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