Results 111 to 120 of about 200,780 (234)

Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis

Cell Reports
Summary: Glutamine homeostasis plays a crucial role in fundamental cellular processes and is often dysregulated in cancer cells; however, the underlying mechanisms governing this homeostasis remain unclear.
Siyi Li, Ting Ling, Yuhan Wang, Jing Shi, Qiuping Wang, Jing Lv, Jinghan Li, Yu Liu, Yi Zhang, Changhao Liu, Tian Xia, Di Chen, Wenqi Wang, Hong-Xu Liu, Hai-long Piao   +14 more
doaj   +1 more source

Streamlined rAAV HeLaS3 producer cell line generation via GS selection

Scientific Reports
The high cost and complexity of manufacturing recombinant adeno-associated virus vectors continue to limit the broader application of gene therapies, which offer life-changing potential for individuals affected by genetic diseases.
Mariana Antunes, Filipa Moura, Ivy Rose Sebastian, Paula Alves, Patrícia Gomes-Alves, Jose M. Escandell   +5 more
doaj   +1 more source

Regulation of chicken retinal glutamine synthetase during development. [PDF]

, 1989
Regulation of chicken retinal glutamine synthetase during ...
Gerald. Patejunas (7964765)
core  

Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points

JHEP Reports
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj   +1 more source

Neurones express glutamine synthetase when deprived of glutamine or interaction with astrocytes [PDF]

, 2010
P>Glutamine synthetase (GS) forms glutamine by catalyzing the ATP-dependent amidation of glutamate. In healthy brains, GS is restricted to astrocytes but in Alzheimer's disease and cell culture, GS has been detected in ...
Alfons Lawen (3833179), Ralf Dringen (72285), Samantha Fernandes (6102338), Stephen Robinson (18025570)   +3 more
core  

Glutamine Synthetase

Journal of Biological Chemistry, 1972
Jean E. Vorhaben, James W. Campbell
openaire   +1 more source

The isolation and characterization of a cDNA clone encoding Lupinus angustifolius root nodule glutamine synthetase [PDF]

Glutamine synthetase, purified from Lupinus angustifolius legume nodules, was carboxymethylated and succinylated prior to chemical or enzymatic cleavage. Peptides were purified and sequenced.
Grant, Murray, Carne, Alan, Hill, Diana F., Farnden, Kevin J. F.   +3 more
core   +1 more source

Glutamine synthetase [PDF]

Archives of Biochemistry and Biophysics, 1963
openaire   +4 more sources

Pivotal role of glutamine synthetase in ammonia detoxification

Hepatology, 2017
T. Hakvoort, Youji He, W. Kulik, J. Vermeulen, Suzanne Duijst, J. Ruijter, J. Runge, N. Deutz, S. E. Koehler, W. Lamers   +9 more
semanticscholar   +1 more source

Glutamine synthetase: a tumor suppressor in hepatocellular carcinoma? [PDF]

J Mol Cell Biol, 2023
Dai W, Zong WX.
europepmc   +1 more source