Results 91 to 100 of about 200,780 (234)

Blockade of glutamine synthetase enhances inflammatory response [PDF]

, 2018
Blockade of glutamine synthetase enhances inflammatory ...
Alessio Menga, E. M. Palmieri, D. A Butterfield, D. C. Hooper, M. Mazzone, A Castegna, A. Lebrun   +6 more
core  

Cloning and expression of murine glutamine synthetase. [PDF]

, 1989
Cloning and expression of murine glutamine ...
Scott Randell. Magnuson (7997663)
core  

Regulation of the spatiotemporal pattern of expression of the glutamine synthetase gene [PDF]

, 1998
Glutamine synthetase, the enzyme that catalyzes the ATP-dependent conversion of glutamate and ammonia into glutamine, is expressed in a tissue-specific and developmentally controlled manner.
Lamers, W. H., Hakvoort, T. B., Heleen Lie-Venema, Lie-Venema, H., Wouter H. Lamers, Formijn J. van Hemert, Moorman, A. F., van Hemert, F. J., Antoon F.M. Moorman, Theodorus B.M. Hakvoort   +9 more
core   +1 more source

Metabolic regulation of ammonia emission in different senescence phenotypes of Nicotiana tabacum

Biologia Plantarum, 2016
In order to reveal the character of ammonia emission in senescent tobacco (Nicotiana tabacum), the content of NH4 +, total nitrogen, and soluble protein, and the activities of nitrogen metabolism-related enzymes were measured in leaves of a quick-leaf ...
Y. J. Wu, T. Z. Yang, Y. Y. Song, X. Q. Zhang, S. X. Xu, G. Xue, X. X. Xing   +6 more
doaj   +1 more source

Astrocytes and glutamate homoeostasis in Alzheimer's disease: a decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex

ASN Neuro, 2013
Astrocytes control tissue equilibrium and hence define the homoeostasis and function of the CNS (central nervous system). Being principal homoeostatic cells, astroglia are fundamental for various forms of neuropathology, including AD (Alzheimer's disease)
Magdalena Kulijewicz-Nawrot, E. Sykova, A. Chvátal, A. Verkhratsky, Jose Julio Rodriguez   +4 more
semanticscholar   +1 more source

Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-l-glutamate/glutamine cell wall structure, and bacterial replication [PDF]

, 2000
New antibiotics to combat the emerging pandemic of drug-resistant strains of Mycobacterium tuberculosis are urgently needed. We have investigated the effects on M.
Harth, Günter, Zamecnik, Paul C, Tabatadze, David, Tang, Jin-Yan, Horwitz, Marcus A   +4 more
core   +1 more source

Regulation of Astrocyte Glutamine Synthetase in Epilepsy

Neurochemistry International, 2013
Astrocytes play a crucial role in regulating and maintaining the extracellular chemical milieu of the central nervous system under physiological conditions. Moreover, proliferation of phenotypically altered astrocytes (a.k.a.
T. Eid, Nathan Tu, Tih‐Shih W Lee, J. Lai   +3 more
semanticscholar   +1 more source

Glutamine replenishment and ammonia removal in hybridoma cell cultures via immobilized glutamine synthetase [PDF]

, 1999
Hybridoma cells utilize glutamine as their primary nitrogen source and excrete ammonia as a metabolic waste product. This ammonia can quickly accumulate to toxic levels in hybridoma culture media, and can severely reduce monoclonal antibody production ...
Okeson, Carl D.
core  

Hepatic glutamine synthetase deficiency in fatal hyperammonemia after lung transplantation. [PDF]

, 1997
BACKGROUND: The cause of severe acquired hyperammonemia, an uncommon but often fatal complication of organ transplantation and chemotherapy for cancer, is obscure.
McCann, M T, Berry, G T, Rajagopal, B S, Lichtenstein, G R, Tuchman, M, Bavaria, Joseph E, MD, Furth, E E, Gibson, J B, Kaplan, P B   +8 more
core  

The Overexpression of Glutamine Synthetase in Transgenic Poplar: A Review [PDF]

, 2006
In investigating the pivotal role of glutamine synthetase in woody plant development, we have strived to develop an understanding of the biochemical and physiological mechanisms whereby enhanced expression of glutamine synthetase (GS) in poplar ...
R. El-Khatib, H. Man, E. G. Kirby, F. Gallardo   +3 more
core   +1 more source