Results 81 to 90 of about 87,161 (272)

The role of glutamine synthetase expression and cystine/glutamate transporter (SLC7A11, xCT) in epilepsy pathogenesis of patients with supratentorial brain gliomas

Эпилепсия и пароксизмальные состояния, 2022
Background. Epileptic seizures represent one of the leading clinical manifestations of glial brain tumors that develop on average in 51% of cases. In gliomas, epileptogenesis is quite complex and multifactorial.Objective: to study a role of the expressed
M. Yu. Prokudin, B. V. Martynov, A. I. Yakovenko, I. V. Litvinenko, V. Yu. Lobzin, D. V. Svistov, V. S. Chirskiy, K. A. Chemodakova, O. А. Klitsenko   +8 more
doaj   +1 more source

Effect of the nitrogen source on glutamine and alanine biosynthesis in Neurospora crassa. An in vivo 15N nuclear magnetic resonance study [PDF]

, 1982
The influences of different nitrogen sources on the relative rates of biosynthesis of glutamine and alanine have been studied by 15N nuclear magnetic resonance spectroscopy of intact Neurospora crassa mycelia suspensions.
Kanamori, Keiko, Legerton, Timothy L., Roberts, John D., Weiss, Richard L.   +3 more
core  

The response of diatom central carbon metabolism to nitrogen starvation is different from that of green algae and higher plants [PDF]

, 2011
The availability of nitrogen varies greatly in the ocean and limits primary productivity over large areas. Diatoms, a group of phytoplankton that are responsible for about 20% of global carbon fixation, respond rapidly to influxes of nitrate and are ...
Hockin, Nicola Louise, Kopriva, Stanislav, Malin, Gill, Mock, Thomas, Mulholland, Francis   +4 more
core   +1 more source

Biostimulant Effects of Seed-Applied Sedaxane Fungicide: Morphological and Physiological Changes in Maize Seedlings [PDF]

, 2017
Most crops are routinely protected against seed-born and soil-borne fungal pathogens through seed-applied fungicides. The recently released succinate dehydrogenase inhibitor (SDHI), sedaxane®, is a broad-spectrum fungicide, used particularly to control ...
DAL CORTIVO, Cristian, Conselvan, GIOVANNI BATTISTA, Carletti, Paolo, Barion, Giuseppe, Sella, Luca, Vamerali, Teofilo   +5 more
core   +5 more sources

Male proband with intractable seizures and a de novo start-codon-disrupting variant in GLUL

HGG Advances
Summary: Bi-allelic variants in GLUL, encoding glutamine synthetase and responsible for the conversion of glutamate to glutamine, are associated with a severe recessive disease due to glutamine deficiency.
Elizabeth Carbonell, Sarah L. Stenton, Vijay S. Ganesh, Jialan Ma, Grace E. VanNoy, Lynn Pais, John N. Gaitanis, Melanie C. O’Leary, Heidi L. Rehm, Anne O’Donnell-Luria   +9 more
doaj   +1 more source

Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine

Microbial Cell Factories, 2020
Background l-Alanyl-l-glutamine (AQ) is a functional dipeptide with high water solubility, good thermal stability and high bioavailability. It is widely used in clinical treatment, post-operative rehabilitation, sports health care and other fields. AQ is
Jiangming Zhu, Wei Yang, Bohua Wang, Qun Liu, Xiaotong Zhong, Quanxiu Gao, Jiezheng Liu, Jianzhong Huang, Baixue Lin, Yong Tao   +9 more
doaj   +1 more source

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Astrocytes and Glutamine Synthetase in Epileptogenesis [PDF]

Journal of Neuroscience Research, 2018
AbstractThe cellular, molecular, and metabolic mechanisms that underlie the development of mesial temporal lobe epilepsy are incompletely understood. Here we review the role of astrocytes in epilepsy development (a.k.a. epileptogenesis), particularly astrocyte pathologies related to: aquaporin 4, the inwardly rectifying potassium channel Kir4.1 ...
Tore Eid, Tih‐Shih W. Lee, Peter Patrylo, Hitten P. Zaveri   +3 more
openaire   +2 more sources

Effects of CO2 enrichment on photosynthesis, growth, and nitrogen metabolism of the seagrass Zostera noltii [PDF]

, 2012
Seagrass ecosystems are expected to benefit from the global increase in CO2 in the ocean because the photosynthetic rate of these plants may be C-i-limited at the current CO2 level.
Alexandre, Alexandre, Amthor, Andría, Beer, Beer, Cabaço, Caldeira, Corzo, Cousins, Duarte, Duarte, Feely, Fonseca, Furbank, Gao, Gao, García-Sánchez, Gattuso, Genty, Gordillo, Guinotte, Hall-Spencer, Hemminga, Invers, IPCC (Intergovernmental Panel on Climate Change), Jassby, Jiang, Liu, Magnusson, Marschner, Mercado, Mercado, Palacios, Parsons, Pelletier, Peralta, Porzio, Pörtner, Riebesell, Sagi, Santos, Semesi, Silva, Silva, Stitt, Taiz, Thom, Touchette, Ullrich, Vessey, Xu, Yelle, Zieman, Zimmerman, Zimmerman, Zou   +56 more
core   +1 more source

Genetic code expansion for chemosensing and chemical actuation of biological functions

Bulletin of the Korean Chemical Society, EarlyView.
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley   +1 more source