Results 71 to 80 of about 119,068 (185)

Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis

Cell Reports
Summary: Glutamine homeostasis plays a crucial role in fundamental cellular processes and is often dysregulated in cancer cells; however, the underlying mechanisms governing this homeostasis remain unclear.
Siyi Li, Ting Ling, Yuhan Wang, Jing Shi, Qiuping Wang, Jing Lv, Jinghan Li, Yu Liu, Yi Zhang, Changhao Liu, Tian Xia, Di Chen, Wenqi Wang, Hong-Xu Liu, Hai-long Piao   +14 more
doaj   +1 more source

Streamlined rAAV HeLaS3 producer cell line generation via GS selection

Scientific Reports
The high cost and complexity of manufacturing recombinant adeno-associated virus vectors continue to limit the broader application of gene therapies, which offer life-changing potential for individuals affected by genetic diseases.
Mariana Antunes, Filipa Moura, Ivy Rose Sebastian, Paula Alves, Patrícia Gomes-Alves, Jose M. Escandell   +5 more
doaj   +1 more source

Blockade of glutamine synthetase enhances inflammatory response

, 2018
Blockade of glutamine synthetase enhances inflammatory ...
Alessio Menga, E. M. Palmieri, D. A Butterfield, D. C. Hooper, M. Mazzone, A Castegna, A. Lebrun   +6 more
core   +1 more source

Heterogeneous distribution of glutamine synthetase during rat liver development

, 1987
Two days before birth, immunohistochemical detection of glutamine synthetase already reveals a heterogeneous distribution pattern related to the vascular architecture of the liver.
G H ten Voorde, Lamers, W. H., R Charles, Gaasbeek Janzen, J. W., W H Lamers, ten Voorde, G. H., Gebhardt, R., A F Moorman, Charles, R., Moorman, A. F., R Gebhardt, J W Gaasbeek Janzen   +11 more
core   +1 more source

Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points

JHEP Reports
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj   +1 more source

Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation [PDF]

, 2010
During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
core  

Gene expression, cellular localisation and function of glutamine synthetase isozymes in wheat (Triticum aestivum L.)

, 2008
We present the first cloning and study of glutamine synthetase (GS) genes in wheat (Triticum aestivum L.). Based on sequence analysis, phylogenetic studies and mapping data, ten GS sequences were classified into four sub-families: GS2 (a, b and c), GS1 ...
Foyer, C. H., Bernard, Stéphanie M., Jahn, Thomas P, Tercé-Laforgue, Thérèse, Parry, M. A. J., Forde, Brian G., Schjørring, Jan Kofod, Dubois, Frederic, Kichey, Thomas, Habash, D. Z., Forde, Brian G, Dionisio, Giuseppe, Jahn, T. P., Baudo, Marcela, Araus, J. L., Parry, Martin A.J., Araus, Jose Luis, Moller, A. L. B., Terce-Laforgue, T., Hirel, Bertrand, Dubois, F., Schjoerring, Jan K, Lopes, M. S., Møller, Anders Laurell Blom, Foyer, Christine H., Bernard, S. M., Bernard, Stéphanie M, Parry, Martin A J, Jahn, Thomas Paul, Lopes, Marta S, Kichey, T., Dionisio, G., Schjoerring, J. K., Foyer, Christine H, Lopes, Marta S., Baudo, M., Hirel, B., Habash, Dimah Z., Forde, B. G., Habash, Dimah Z   +39 more
core   +1 more source

Glutamine synthetase and heteroresistance in methicillin-resistant Staphylococcus aureus.

, 1996
Inactivation of femC in methicillin-resistant Staphylococcus aureus (MRSA) results in lowered methicillin resistance and a reduction in the amidation of the iso-D-glutamate of the peptidoglycan stem peptide.
Strandén AM, Roos M, Berger-Bächi B
core   +1 more source

Glutamine Synthetase

Journal of Biological Chemistry, 1972
Jean E. Vorhaben, James W. Campbell
openaire   +1 more source

Hepatic glutamine synthetase deficiency in fatal hyperammonemia after lung transplantation.

, 1997
BACKGROUND: The cause of severe acquired hyperammonemia, an uncommon but often fatal complication of organ transplantation and chemotherapy for cancer, is obscure.
McCann, M T, Berry, G T, Rajagopal, B S, Lichtenstein, G R, Tuchman, M, Bavaria, Joseph E, MD, Furth, E E, Gibson, J B, Kaplan, P B   +8 more
core   +1 more source