Results 71 to 80 of about 200,780 (234)

Gene expression, cellular localisation and function of glutamine synthetase isozymes in wheat (Triticum aestivum L.) [PDF]

, 2008
We present the first cloning and study of glutamine synthetase (GS) genes in wheat (Triticum aestivum L.). Based on sequence analysis, phylogenetic studies and mapping data, ten GS sequences were classified into four sub-families: GS2 (a, b and c), GS1 ...
Foyer, C. H., Bernard, Stéphanie M., Jahn, Thomas P, Tercé-Laforgue, Thérèse, Parry, M. A. J., Forde, Brian G., Schjørring, Jan Kofod, Dubois, Frederic, Kichey, Thomas, Habash, D. Z., Forde, Brian G, Dionisio, Giuseppe, Jahn, T. P., Baudo, Marcela, Araus, J. L., Parry, Martin A.J., Araus, Jose Luis, Moller, A. L. B., Terce-Laforgue, T., Hirel, Bertrand, Dubois, F., Schjoerring, Jan K, Lopes, M. S., Møller, Anders Laurell Blom, Foyer, Christine H., Bernard, S. M., Bernard, Stéphanie M, Parry, Martin A J, Jahn, Thomas Paul, Lopes, Marta S, Kichey, T., Dionisio, G., Schjoerring, J. K., Foyer, Christine H, Lopes, Marta S., Baudo, M., Hirel, B., Habash, Dimah Z., Forde, B. G., Habash, Dimah Z   +39 more
core   +1 more source

The Unexpected Essentiality of glnA2 in Mycobacterium smegmatis Is Salvaged by Overexpression of the Global Nitrogen Regulator glnR, but Not by L-, D- or Iso-Glutamine

Frontiers in Microbiology, 2018
Nitrogen metabolism plays a central role in the physiology of microorganisms, and Glutamine Synthetase (GS) genes are present in virtually all bacteria. In M.
Nadya Rakovitsky, Michal Bar Oz, Karin Goldberg, Simon Gibbons, Oren Zimhony, Oren Zimhony, Daniel Barkan   +6 more
doaj   +1 more source

Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Nature Cell Biology, 2015
L-Glutamine (Gln) functions physiologically to balance the carbon and nitrogen requirements of tissues. It has been proposed that in cancer cells undergoing aerobic glycolysis, accelerated anabolism is sustained by Gln-derived carbons, which replenish ...
S. Tardito, A. Oudin, S. Ahmed, F. Fack, O. Keunen, Liang Zheng, H. Miletic, P. Sakariassen, Adam Weinstock, Allon Wagner, Susan L. Lindsay, A. Hock, S. Barnett, E. Ruppin, S. H. Mørkve, M. Lund-Johansen, A. Chalmers, R. Bjerkvig, S. Niclou, E. Gottlieb   +19 more
semanticscholar   +1 more source

Eucalyptus ESTs corresponding to the enzyme glutamine synthetase and the protein D1, sites of action of herbicides that cause oxidative stress

Genetics and Molecular Biology, 2005
This work was aimed at locating Eucalyptus ESTs corresponding to the GS enzyme (Glutamine Synthetase, EC = 6.3.1.2) and to the D1 protein, which are directly related to resistance to herbicides that promote oxidative stress.
Edivaldo Domingues Velini, Maria Lúcia Bueno Trindade, Elza Alves, Ana Catarina Catâneo, Celso Luis Marino, Ivan de Godoy Maia, Edson Seizo Mori, Edson Luiz Furtado, Iraê Amaral Guerrini, Carlos Frederico Wilcken   +9 more
doaj   +1 more source

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

Nature, 2020
Muscle regeneration is sustained by infiltrating macrophages and the consequent activation of satellite cells 1 – 4 . Macrophages and satellite cells communicate in different ways 1 – 5 , but their metabolic interplay has not been investigated.
Min Shang, Federica Cappellesso, Ricardo Amorim, J. Serneels, Federico Virga, G. Eelen, S. Carobbio, M. Y. Rincon, P. Maechler, K. de Bock, Ping-Chih Ho, M. Sandri, B. Ghesquière, P. Carmeliet, Mario Di Matteo, E. Berardi, M. Mazzone   +16 more
semanticscholar   +1 more source

Macrophage Stimulated by Low Ambient Temperature Hasten Tumor Growth via Glutamine Production

Biomedicines, 2020
Ambient temperature can regulate the immune response and affect tumor growth. Although thermoneutral caging reduces tumor growth via immune activation, little attention has been paid to the tumorigenic effect of low temperature.
Eun-Ji Lee, Tae-Wook Chung, Keuk-Jun Kim, Boram Bae, Bo-Sung Kim, Suhkmann Kim, Dongryeol Ryu, Sung-Jin Bae, Ki-Tae Ha   +8 more
doaj   +1 more source

Novel Glutamate–Putrescine Ligase Activity in Haloferax mediterranei: A New Function for glnA-2 Gene

Biomolecules, 2021
The genome of the halophilic archaea Haloferax mediterranei contains three ORFs that show homology with glutamine synthetase (GS) (glnA-1, glnA-2, and glnA-3).
Verónica Rodríguez-Herrero, Arnau Peris, Mónica Camacho, Vanesa Bautista, Julia Esclapez, María-José Bonete   +5 more
doaj   +1 more source

Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation

Cell Metabolism, 2015
Summary c-Myc is known to promotes glutamine usage by up-regulating glutaminase (GLS), which converts glutamine to glutamate that is catabolized in the TCA cycle. Here we report that in a number of human and murine cells and cancers, Myc induces elevated
Alex J. Bott, I-Chen Peng, Yongjun Fan, B. Faubert, Lu Zhao, Jinyu Li, Sarah Neidler, Yu Sun, N. Jaber, Dawid Krokowski, Wenyun Lu, Ji-An Pan, Scott Powers, Joshua D. Rabinowitz, M. Hatzoglou, Daniel J. Murphy, Russell G. Jones, Song Wu, G. Girnun, W. Zong   +19 more
semanticscholar   +1 more source

Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles [PDF]

, 1986
The regulation of glutamine synthetase by glucocorticoids in rat skeletal muscles was studied. Administration of dexamethasone strikingly enhanced glutamine synthetase activity in plantaris and soleus muscles.
Vitkovic, Ljubisa, Max, Stephen R., Banner, Carl, Konagaya, Masaaki, Konagaya, Yoko, Thomas, John W.   +5 more
core   +1 more source

The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain

Neuroscience Letters, 2015
Highlights • Nuclear FOXO3a significantly correlates with glutamine synthetase expression.• FOXO3a nuclear localisation correlates with a DNA damage response.• Glutamine synthetase expression correlates with increasing Alzheimer pathology.
Adeline Fluteau, P. Ince, T. Minett, F. Matthews, C. Brayne, C. Garwood, L. Ratcliffe, S. Morgan, P. Heath, P. Shaw, S. Wharton, J. Simpson   +11 more
semanticscholar   +1 more source