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Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling
Biochemical and Biophysical Research Communications, 2010Glutaredoxin-1 (GRX-1) is a cytoplasmic enzyme that highly contributes to the antioxidant defense system. It catalyzes the reversible reduction of glutathione-protein mixed disulfides, a process called deglutathionylation. Here, we investigated the role of GRX-1 in the pathway triggered by interleukin-1/Toll-like receptor 4 (IL-1R/TLR4) by using RNA ...
Eleni, Chantzoura +4 more
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The role of monocytic glutaredoxin 1 in atherogenesis.
Atherosclerosis, 2020Y.J. Ahn, L. Wang, R. Asmis
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The role of glutaredoxin-1 in pulmonary inflammation induced by diesel exhaust particles
European Respiratory Journal, 2013Rationale: Inhalation of diesel exhaust particles (DEP) is associated with an oxidative and inflammatory response in the lung (Provoost et al., J Allergy Clin Immunol., 2012, 129: 483-491). Glutaredoxin-1 (GRX1) is a cytosolic enzyme that can regulate redox-dependent signalling cascades and pro-inflammatory ...
Sharen Provoost +6 more
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Glutaredoxin 1 And Protein S-Glutathionylation In COPD
C52. COPD PATHOGENESIS: HUMAN STUDIES, 2012Niki Reynaert +5 more
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Glutaredoxin-1 Regulates Hepatic Lipid Metabolism
Free Radical Biology and Medicine, 2014Di Shao +7 more
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Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia
Free Radical Biology and Medicine, 2015Di Shao +7 more
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Acrolein in Cigarette Smoke Extract Binds to Glutaredoxin 1.
D41. SMOKING HEALTH EFFECTS, 2009I Kuipers +5 more
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Study of the involvement of glutaredoxin 1 in copper homeostasis in neuroblastoma cells
2013Copper (Cu) is a redox transition metal existing in two ionic forms, Cu+ and Cu++. In biological systems the electrochemical properties of copper ions make it an important cofactor for many enzymes that catalyze a wide range of biochemical processes such as oxidative phosphorylation, antioxidant defense, catecholamine synthesis, iron homeostasis and ...
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