Results 111 to 120 of about 11,635 (215)
Diabetes mellitus Typ 2 ist eine chronische Stoffwechselerkrankung, die aufgrund ihrer hohen Prävalenz und schweren Folgeerkrankungen gesundheitliche, gesellschaftliche und wirtschaftliche Relevanz besitzt.
Kreimer, Hanno
core +1 more source
, 2007 Oxidative stress, excitotoxicity and mitochondrial dysfunction play synergistic roles in neurodegeneration. Maintenance of thiol homeostasis is important for normal mitochondrial function and dysregulation of protein thiol homeostasis by oxidative stress
Kenchappa, Rajappa S. +3 more
core +1 more source
Thiol−Disulfide Exchange between Glutaredoxin and Glutathione
, 2016 Glutaredoxins are ubiquitous thiol−disulfide oxidoreductases which catalyze the reduction of glutathione−protein mixed disulfides. Belonging to the thioredoxin family, they contain a conserved active site CXXC motif.
Kristine Steen Jensen (1885651) +4 more
core +2 more sources
Cardiac‐specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure
Physiological Reports, 2019 Growing evidence suggests that redox‐sensitive proteins including glutaredoxins (Grxs) can protect cardiac muscle cells from oxidative stress‐induced damage. Mammalian Grx3 has been shown to be critical in regulating cellular redox states.
Jimmonique Donelson +15 more
doaj +1 more source
, 2006 International audienceThe existence of natural peroxiredoxin–glutaredoxin hybrid enzymes in several bacteria is in line with previous findings indicating that poplar peroxiredoxin II can use glutaredoxin as an electron donor.
Gans, Pierre +6 more
core +1 more source
Glutaredoxin catalysis requires two distinct glutathione interaction sites
, 2017 Glutaredoxins are key players in cellular redox homoeostasis and exert a variety of essential functions ranging from glutathione-dependent catalysis to iron metabolism.
Patricia Begas +4 more
core +1 more source
Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems
, 2003 Our studies in yeast show that there is an essential requirement for either an active thioredoxin or an active glutathione (GSH)-glutaredoxin system for cell viability.
Eleanor W Trotter +3 more
core +1 more source
Novel Glutaredoxin Gene in Soybean Responds to Aluminum Toxicity in Soil
, 2001 Oxidative stress generated by aerobic metabolism or from environmental sources is a major cause of damage to organisms. Aluminum is a major toxin in acidic soils and one proposed source of oxidative stress.
Thomas-Bostic, Kisha D.
core +1 more source
Thiol-Disulfide Exchange between Glutaredoxin and Glutathione
, 2010 Udgivelsesdato: February 2, 2010Glutaredoxins are ubiquitous thiol-disulfide oxidoreductases which catalyze the reduction of glutathione-protein mixed disulfides. Belonging to the thioredoxin family, they contain a conserved active site CXXC motif. The N-
Iversen, Rasmus +4 more
core +1 more source
Structural and dynamic analysis of human glutaredoxin 3
Human glutaredoxin (Grx3) is an essential protein associated with biological functions including embryonic development and immune response, and is involved in human disease such as lung, colon cancer and cardiovascular disorder.
Andrésen, Cecilia, +2 more
core