Results 181 to 190 of about 11,635 (215)

Mammalian glutaredoxin

1997
Abstract Mammalian glutaredoxin was first purified to homogeneity from calf thymus (Luthman et al., 1979; Luthman, Holmgren, 1982), which later enabled determination of the primary structure (Klintrot et al., 1984) demonstrating an active site with the sequence Cys-Pro-Tyr-Cys, identical to that of Escherichia coli glutaredoxin.
H Nakamura, F Aslund, A Holmgren
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Identification of novel targets of cyanobacterial glutaredoxin

Archives of Biochemistry and Biophysics, 2007
Glutaredoxins (Grxs) are small ubiquitous glutathione-disulfide oxidoreductase that reduce disulfide bonds of target proteins and maintain the redox homoeostasis of cells. Disruption of ssr2061 reduced the viability of cells indicated Grx2061 has a protective role against oxidative stress in Synechocystis sp. PCC 6803.
Min, Li, Qing, Yang, Lianwen, Zhang, Han, Li, Yunluan, Cui, Qingyu, Wu   +5 more
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Structure of the rice glutaredoxin (thioltransferase) gene

Gene, 1997
We have isolated the gene encoding a glutaredoxin in rice (Oryza sativa L.) and determined the nucleotide (nt) sequence of about a 4.2 kb long. The cloned gene (gRASC8) was found to contain four exons interrupted by three introns. The first exon begins the ATG translation start codon and the four exons code for a protein composed of 112 amino acids ...
S, Sha, T, Yabushita, K, Minakuchi, T, Masumura, K, Tanaka   +4 more
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Plasmodium falciparum glutaredoxin-like proteins

Biological Chemistry, 2005
Glutaredoxin-like proteins form a new subgroup of glutaredoxins with a serine replacing the second cysteine in the CxxC-motif of the active site. Yeast Grx5 is the only glutaredoxin-like protein studied biochemically so far. We identified and cloned three genes encoding glutaredoxin-like proteins from the malaria parasite Plasmodium falciparum (Pf Glp1,
Marcel, Deponte, Katja, Becker, Stefan, Rahlfs   +2 more
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Thioredoxin and Glutaredoxin

2007
The sections in this article are 1 Introduction 2 NMR of Escherichia coli Thioredoxin 3 NMR of Human Thioredoxin 4 NMR of Escherichia coli Glutaredoxin 5 Acknowledgements 6 Biographical Sketch Related ...
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Redox properties and evolution of human glutaredoxins

Proteins: Structure, Function, and Bioinformatics, 2007
AbstractGlutaredoxins (Grxs) are glutathione‐dependent oxidoreductases that belong to the thioredoxin superfamily catalyzing thiol‐disulfide exchange reactions via active site cysteine residues. Focusing on the human dithiol glutaredoxins having a C‐X‐Y‐C active site sequence motif, the redox potentials of hGrx1 and hGrx2 were determined to be −232 and
Johan, Sagemark, Tobias H, Elgán, Thomas R, Bürglin, Catrine, Johansson, Arne, Holmgren, Kurt D, Berndt   +5 more
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Evolution and diversity of glutaredoxins in photosynthetic organisms

Cellular and Molecular Life Sciences, 2009
The genome sequencing of prokaryotic and eukaryotic photosynthetic organisms enables a comparative genomic study of the glutaredoxin (Grx) family. The analysis of 58 genomes, using a specific motif composed of the active site sequence and of amino acids involved in glutathione binding, led to an updated classification of Grxs into six classes. Only two
Couturier, Jérémy, Jacquot, Jean-Pierre, Rouhier, Nicolas   +2 more
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Immunolocalization of thioredoxin and glutaredoxin in mammalian hypophysis

Molecular and Cellular Endocrinology, 1992
Thioredoxin (TRX) and glutaredoxin (GRX) are two small proteins catalyzing thiol-disulfide oxidoreductions. A role of both proteins in secretory processes has been suggested and recently it has been demonstrated that thioredoxin functions as a growth factor for lymphocytes in cell cultures.
C A, Padilla, E, Martínez-Galisteo, J, López-Barea, A, Holmgren, J A, Bárcena   +4 more
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A revised sequence of calf thymus glutaredoxin

Biochemical and Biophysical Research Communications, 1989
The previously published structure of the glutaredoxin from calf thymus [Klintrot et al., (1984) Eur. J. Biochem. 144, 417-423] was reinvestigated by tandem mass spectrometry and found to have an N-terminal Ac-Ala-Gln-Ala-... sequence and an additional four amino acids inserted between positions 67 and 68.
I A, Papayannopoulos, Z R, Gan, W W, Wells, K, Biemann   +3 more
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Characterization of the Redox Properties of Poplar Glutaredoxin

Antioxidants & Redox Signaling, 2003
The presence of glutaredoxins in plants is now well recognized, but their functions and natural substrates remain largely unknown. Recently, a poplar glutaredoxin has been biochemically characterized and several mutants have been engineered in order to explore its reactivity. This work focuses on some physiological functions of the enzyme. According to
Rouhier, Nicolas, Vlamis-Gardikas, Alexios, Lillig, Christopher Horst, Berndt, Carsten, Schwenn, Jens-Dirk, Holmgren, Arne, Jacquot, Jean-Pierre   +6 more
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