Results 171 to 180 of about 135,439,936 (222)

Structure of the thioredoxin-like domain of yeast glutaredoxin 3 [PDF]

Acta Crystallographica Section D: Biological Crystallography, 2008
Yeast glutaredoxin 3 (Grx3) is a cytosolic protein that regulates the activity of the iron-responsive transcriptional activator Aft1. This member of the monothiol glutaredoxin family contains a thioredoxin-like domain and a glutaredoxin-like domain ...
Caryn E. Outten, Nin N Dingra
exaly   +2 more sources

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Glutaredoxin 1 regulates cholesterol metabolism and gallstone formation by influencing protein S-glutathionylation.

Metabolism: Clinical and Experimental, 2023
OBJECTIVE Cholesterol gallstone disease (CGD) is closely related to cholesterol metabolic disorder. Glutaredoxin-1 (Glrx1) and Glrx1-related protein S-glutathionylation are increasingly being observed to drive various physiological and pathological ...
Yan Xia, Ying Xu, Qin-Hui Liu, Jin-Hang Zhang, Zi-Jing Zhang, Qingyi Jia, Q. Tang, X. Jing, Jia-Hui Li, Jiahao Chen, Yi-Min Xiong, Yanping Li, Jin-Han He   +12 more
semanticscholar   +1 more source

Zebrafish heart development is regulated via glutaredoxin 2 dependent migration and survival of neural crest cells

Redox Biology, 2014
Glutaredoxin 2 is a vertebrate specific oxidoreductase of the thioredoxin family of proteins modulating the intracellular thiol pool. Thereby, glutaredoxin 2 is important for specific redox signaling and regulates embryonic development of brain and ...
Arne Holmgren, Carsten Berndt, Kai Stühler   +2 more
exaly   +2 more sources

Effect of peroxynitrite on glutaredoxin

Human and Experimental Toxicology, 2001
Glutaredoxin is an important enzyme in thiol homeostasis. As a thioltransferase, it reduces oxidized thiols. It also has dehydroascorbate reductase (DHAR) activity to reduce dehydroascorbate (DHA) to ascorbic acid.
G Aykaç-Toker
exaly   +2 more sources

Molecular characterization and serodiagnostic evaluation of the Echinococcus ortleppi recombinant glutaredoxin 1 protein for cystic echinococcosis in buffalo (Bubalus bubalis).

Veterinary parasitology, 2023
Cystic echinococcosis (CE), caused by the metacestode of Echinococcus granulosus sensu lato (s.l.), adversely affects the physiology of the vital organs in which they grow.
K. Yashica, S. Samanta, R. Balaji, V. Jawalagatti, M. Silamparasan, S. Anandu, A. Rialch, S. Gupta, A. Tewari   +8 more
semanticscholar   +1 more source

NF‐κB inactivation attenuates the M1 macrophage polarization in experimental necrotizing enterocolitis by glutaredoxin‐1 deficiency

Cell Biology International, 2022
The pathogenesis of necrotizing enterocolitis (NEC) is severe inflammatory injury in preterm infants, which resulted from macrophage polarization. Nuclear factor‐κB (NF‐κB) is implicated to be involved in macrophage polarization.
Yang Luo, Dan Mo, Hongjie Guo, Cui-Lian Ye, Bailin Chen, Hai Zhu, Chun Deng, Qin Deng, Chun-Bao Guo, Lin Qiu   +9 more
semanticscholar   +1 more source

Inhibition of myeloid HDAC2 upregulates glutaredoxin 1 expression, improves protein thiol redox state and protects against high-calorie diet-induced monocyte dysfunction and atherosclerosis.

Atherosclerosis, 2021
BACKGROUND AND AIMS The thiol transferase glutaredoxin 1 controls redox signaling and cellular functions by regulating the S-glutathionylation status of critical protein thiols.
Lu-Xi Wang, Y. Ahn, R. Asmis
semanticscholar   +1 more source

Structural and stability characteristics of a monothiol glutaredoxin: Glutaredoxin-like protein 1 from Plasmodium falciparum

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2008
Recently discovered monothiol glutaredoxins with CXXS-active site sequence share a common structural motif and biochemical mechanism of action and are involved in multiple cellular functions. Here we report first studies on the structural and stability characterization of a monothiol glutaredoxin, in particular--PfGLP1.
Timir, Tripathi, Stefan, Rahlfs, Katja, Becker, Vinod, Bhakuni   +3 more
openaire   +2 more sources

Abstract 13989: Glutaredoxin-1: A Redox Regulator of Metalloproteases in Vascular Endothelial Cells

Circulation, 2022
Background: Endothelial dysfunction is a common mediator of aneurysmal remodeling regardless of etiology and the vascular bed that occur (e.g., genetic mutations, hypertension, aging, smoking, abdominal or thoracic artery or aortic root), but the ...
Jing-Yan Han, Hanxiao Liu, Yuko Tsukahara, Xue-Ping Wan, Sandra Sulser Ponce De Leon, Enkhjargal Budbazar, F. Seta   +6 more
semanticscholar   +1 more source

Microalgal glutaredoxin 1 interacts with transcription factor bZIP to resist cadmium stress via lipid metabolism alteration.

Bioresource Technology
Triacylglycerol (TAG), a universal energy reserve and biodiesel feedstock, accumulates under stress in microalgae. However, the regulatory mechanisms linking stress signals to TAG synthesis remain unclear.
Chao Xing, Xuan Fu, Yaru Du, Kui Liu, Hong-Li Yuan, Jin Liu, Jin-Shui Yang   +6 more
semanticscholar   +1 more source