Results 11 to 20 of about 88,346 (287)

A glutathione s-transferase confers herbicide tolerance in rice [PDF]

Crop Breeding and Applied Biotechnology, 2014
Plant glutathione S-transferases (GSTs) have been a focus of attention due to their role in herbicide detoxification. OsGSTL2 is a glutathione S-transferase, lambda class gene from rice (Oryza sativa L.).
Tingzhang Hu
doaj   +4 more sources

The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells [PDF]

, 1989
The distribution and inducibility of cytosolic glutathione S-transferase (EC 2.5.1.18) and glutathione peroxidase (EC 1.11.1.19) activities in rat liver parenchymal, Kupffer and endothelial cells were studied.
Pablo Steinberg, Helga Schramm, Ludwig Schladt, Larry W. Robertson, Helmut Thomas, Franz Oesch   +5 more
openalex   +4 more sources

Relationship Between Alpha+-Thalassaemia and Glutathione-S-Transferases Polymorphisms in Children with Severe Malaria in Tanzania [PDF]

, 2013
Alpha+-thalassaemia is well known for conferring partial protection to against severe malaria. On the other, Glutathione –S-transferase (GST) polymorphism has recently been associated to severe malaria in children.
Balthazary, Sakurani, Francis, Filbert, Manjurano, Alphaxard, Max, Robert, Saguti, Fredy, Tenu, Filemon   +5 more
core   +1 more source

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia [PDF]

, 2001
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens.
Allan, J.M., Wild, C.P., Rollinson, S., Willett, E.V., Moorman, A.V., Dovey, G.J., Roddam, P.L., Roman, E., Cartwright, R.A., Morgan, G.J.   +9 more
core   +7 more sources

Hoverfly glutathione S-transferases and effect of Brassicaceae secondary metabolites [PDF]

, 2001
The Episyrphus balteatus hoverfly is commonly found in very diversified biotopes including Brassicaceae crop fields. Glutathione S-transferases (GST) are detoxification enzymes that are involved in the metaboliza-tion of plant allelochemicals such as ...
Francis, Frédéric, Haubruge, Eric, Lognay, Georges, Vanhaelen, Nicolas   +3 more
core   +2 more sources

Effect of gene-gene and gene-environment interactions associated with antituberculosis drug-induced hepatotoxicity [PDF]

, 2017
This study evaluated the association between environmental factors and genetic variations in enzymes that metabolize antituberculosis (anti-TB) drugs [arylamine N-acetyltransferase 2, cytochrome P450 2E1 (CYP2E1), glutathione S-transferase theta 1 (GSTT1)
Aidar, O., Caradonna, F., Castagnino, J., Chamorro, J., Costa, L., de Larra\uf1aga, G., Fr\uedas, A., Musella, R., Nogueras, M., Perez, A., Visca, M.   +10 more
core   +1 more source

Prostate cancer and glutathione S-transferase deletions [PDF]

, 2015
GSTM1 and GSTT1 gene polymorphisms have been studied in many populations to evaluate their association with prostate cancer risk with contrasting results.
Malik, Saima Shakil, Masood, Nosheen, Yasmin, Azra   +2 more
core   +1 more source

Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines [PDF]

, 2014
BACKGROUND: Chemotherapy response in ovarian cancer patients is frequently compromised by drug resistance, possibly due to altered drug metabolism. Platinum drugs are metabolised by glutathione S-transferase P1 (GSTP1), which is abundantly, but variably ...
A De Luca, A Eastman, AD Lewis, B R Ihrig, BC Behrens, C Peklak-Scott, C R Wolf, C Sachse, CJ Henderson, D Hagrman, DF Dourado, DM Townsend, E Kolwijck, EA Boss, F Ali-Osman, G Cheng, G Konecny, G Ricci, G Scambia, G Smith, G Smith, GB Kristensen, GK Smyth, H C Young, H Kase, H Kuroda, H Parekh, H Yanagie, J Chen, J Chen, JD Hayes, JT Ahokas, JX Yang, K Satoh, K Tozawa, KD Tew, KH Sun, L Galluzzi, L Li, L Sawers, LA Rosario, LI McLellan, LW Harries, M J Ferguson, MH Lyttle, N Ban, P Chakravarty, P Saip, P Surowiak, P Turella, P Zimniak, PG Board, R Elsby, S Kotoh, S Vaughan, SM Black, SM Black, T Mosmann, TC Shea, TM Ishimoto, V Adler, V Anathy, X Zhang, Y Mizutani, Y Wang, Y Wu, YY Wang, Z Yin   +67 more
core   +2 more sources

Method of identifying inhibitors of glutathione S-transferase (GST) gene expression [PDF]

, 1999
Complementary DNA and genomic clones for three variants of GST-.pi. are disclosed. It is demonstrated that certain of these variants are overexpressed in gliomas, thereby indicating an involvement with that form of cancer.
Akande, Olanike, Ali-Osman, Francis, Antoun, Gamil, Buolamwini, John K., Keller, Charles W., Lo, Hui-Wen, Lopez-Berestein, Gabriel   +6 more
core   +1 more source

Reversal of hypermethylation and reactivation of glutathione -transferase pi 1 gene by curcumin in breast cancer cell line

Tumor Biology, 2017
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar, Ujjawal Sharma, Garima Rathi   +2 more
doaj   +1 more source