Results 111 to 120 of about 569,398 (304)
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
, 2019 In an attempt to develop an imaging probe with ultra-high sensitivity for a broad range of tumors in vivo and inspired by the concept of chemical synthetic nanoreactors, we designed a type of glutathione-priming fluorescent nanoreactor (GPN) with an ...
Zhao Li (300229) +12 more
core +1 more source
Advanced Science, EarlyView.Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu +4 more
wiley +1 more source
Фармакокинетика и Фармакодинамика, 2016 We studied the pharmacokinetic parameters of N-acetylcysteine at a single oral and intravenous administration of healthy volunteers. Elimination half-life (t1/2) within 2 hours and the maximum concentration in blood (Cmax) after 1 hour after ...
A. A. Dutov +5 more
doaj
CellsChondroitin sulfate (CS) chains on the cell surface are sulfated in various patterns, and this structure is the basis of CS function. We aimed to investigate the role of chondroitin 4-O-sulfotransferase-1 (C4ST-1), the enzyme responsible for the 4 ...
Satomi Nadanaka +4 more
doaj +1 more source
Glutathione biosynthesis pathway and glutathione-ascorbate cycle.
, 2018 For the figure legend refers to Fig 2. Abbreviations: SOD Superoxide dismutase; CAT Catalase; APX Ascorbate peroxidase (not annotated); MDHA monodehydroascorbate; MDHAR monodehydroascorbate reductase; DHA dehydroascorbate; DHAR dehydroascorbate reductase;
Lenny de Jaeger (5100551) +7 more
core +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
AnimalsIn vitro maturation (IVM) of oocytes is a pivotal step in assisted reproductive technologies for livestock. However, oxidative stress (OS) and mitochondrial dysfunction during in vitro culture often lead to oocyte aging, thereby limiting the efficiency ...
Xingyu Zhang +6 more
doaj +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Frontiers in PharmacologySepsis remains a major global health challenge, exerting a particularly severe toll in low- and middle-income countries. Despite advances in antimicrobial and supportive care, sepsis continues to defy effective control due to its complex pathophysiology ...
Yijuan Lin +3 more
doaj +1 more source