Surface modified sulfur nanoparticles can escape the glutathione reductase mediated detoxification system in fungi [PDF]
The antifungal effects of orthorhombic (~10 nm; spherical) and monoclinic (~50 nm; tetrapod) sulfur nanoparticles (SNPs) were studied against the NADPH-dependent glutathione reductase (GR) mediated xenobiotic detoxification system (GSH-GSSG) in filamentous fungi (Aspergillus niger as a model organism).
arxiv
The Oxidative Stress and Platelet Activation in Patients Infected with Toxoplasma gondii
Background: Toxoplasma gondii is a highly frequent obligate intracellular protozoan parasite; it can cause serious problems to the public health especially pregnant females, however, the pathogenesis of this condition is not clear.
Hoda AM Hamdy+3 more
doaj +1 more source
MXene 3D/4D Printing: Ink Formulation and Electrochemical Energy Storage Applications
A comprehensive study of MXene printing technique is presented, focusing on MXene ink formulation, surface chemistry, rheological characteristics, physical storage, and ink stability. Different printing techniques, such as 3D/4D printing, screen printing, inkjet printing, and continuous liquid interface production printing along with their applications
Shaista Nouseen, Martin Pumera
wiley +1 more source
Bistable equilibrium points of mercury body burden [PDF]
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion of mercury (we refer to \cite{Thim05}, \cite{ZalBar99} and \cite{Lyn02}).
arxiv
Glutathione protects liver and kidney tissue from cadmium- and lead-provoked lipid peroxidation [PDF]
Cd and Pb represent a serious ecological problem due to their soluble nature, their mobility and ability to accumulate in the soil. The exposure to these heavy metals can originate from different sources (drinking water, food, air), and they can make ...
Jovanović Jasmina M.+4 more
doaj +1 more source
Cell Membrane Vesicle Camouflaged Artificial Cells
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres+11 more
wiley +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie+8 more
wiley +1 more source
Intracellular Glutathione Depletion by Oridonin Leads to Apoptosis in Hepatic Stellate Cells
Proliferation of hepatic stellate cells (HSCs) plays a key role in the pathogenesis of liver fibrosis. Induction of HSC apoptosis by natural products is considered an effective strategy for treating liver fibrosis.
Liang-Mou Kuo+5 more
doaj +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
The growth and development of non-small cell lung cancer (NSCLC) primarily depends on glutamine. Both glutamine and essential amino acids (EAAs) have been reported to upregulate mTOR in NSCLC, which is a bioenergetics sensor involved in the regulation of
Lichchavi Dhananjaya Rajasinghe+2 more
doaj +1 more source