Results 71 to 80 of about 775,294 (358)
Glutathione: Overview of its protective roles, measurement, and biosynthesis
Molecular Aspects of Medicine, 2008 This review is the introduction to a special issue concerning, glutathione (GSH), the most abundant low molecular weight thiol compound synthesized in cells.
H. Forman, Hongqiao Zhang, A. Rinna
semanticscholar +1 more source
The role of glutathione transferases in TNT detoxification [PDF]
, 2012 Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
core
, 2003 The acclimation of reduced glutathione (GSH) biosynthesis and GSH-utilizing enzymes to salt stress was studied in two tomato species that differ in stress tolerance. Salt increased GSH content and GSH:GSSG (oxidized glutathione) ratio in oxidative stress-
Guy Kiddle +23 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
AntioxidantsFLASH radiotherapy is a novel irradiation modality that employs ultra-high mean dose rates exceeding 40–150 Gy/s, far surpassing the typical ~0.03 Gy/s used in conventional radiotherapy.
Israth Rabeya +2 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Glutathione and Glutathione Delivery Compounds
, 1996 Deficiency of GSH (BSO model) demonstrates the need for cellular protection from endogenous ROS. The pathology of various diseases is often associated with ROS and oxidative stress. The several methods for modulating cellular GSH levels presented in this chapter offer selective tools to study mechanisms and offer potential therapy of human diseases ...
openaire +2 more sources
Reductive stress in mitochondria isolated from the carotid body of type 1 diabetic male Wistar rats
Physiological ReportsThe carotid body (CB) senses changes in arterial O2 partial pressure (pO2) and glucose levels; therefore, it is key for the detection of hypoxia and hypoglycemia. The CB has been suggested to detect pO2 through an increase in reactive oxygen species (ROS)
Hector R. Tejeda‐Chavez +5 more
doaj +1 more source
MXene Wrapped Magnetic Mesocrystals for Durable Redox Catalytic Cancer Therapy and Responsive MRI
Advanced Functional Materials, EarlyView.Conformal wrapping of ultrathin Ti3C2Tx MXene nanosheets on Fe3O4 mesocrystals creates topology‐stabilized Schottky junctions that direct photoinduced electron transfer under NIR irradiation. The unique architecture sustains Fenton catalysis, promotes continuous hydroxyl radical production, and provides photo‐responsive MRI contrast.
Min Jun Ko +10 more
wiley +1 more source
An In Vitro Study of Protein S-Glutathionylation by Members of the CLIC Protein Family
BiomoleculesIncreasing evidence points to members of the chloride intracellular ion channel (CLIC) protein family performing a variety of functions within cells—classifying them as moonlighting proteins—and serving as natural cellular antioxidant protective agents ...
Wendy El Khoury +4 more
doaj +1 more source