Results 71 to 80 of about 569,398 (304)

Reductive stress in mitochondria isolated from the carotid body of type 1 diabetic male Wistar rats

Physiological Reports
The carotid body (CB) senses changes in arterial O2 partial pressure (pO2) and glucose levels; therefore, it is key for the detection of hypoxia and hypoglycemia. The CB has been suggested to detect pO2 through an increase in reactive oxygen species (ROS)
Hector R. Tejeda‐Chavez, Sergio Montero, Alfredo Saavedra‐Molina, Monica Lemus, Julio B. Tejeda‐Luna, Elena Roces de Alvarez‐Buylla   +5 more
doaj   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

An In Vitro Study of Protein S-Glutathionylation by Members of the CLIC Protein Family

Biomolecules
Increasing evidence points to members of the chloride intracellular ion channel (CLIC) protein family performing a variety of functions within cells—classifying them as moonlighting proteins—and serving as natural cellular antioxidant protective agents ...
Wendy El Khoury, Khondker Rufaka Hossain, Amani Alghalayini, Hala M. Ali, Stella M. Valenzuela   +4 more
doaj   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

The Role of Glutathione Transferases in the Detoxification of TNT [PDF]

, 2010
Manufacture, use, storage and improper disposal of the explosive 2,4,6-trinitrotoluene (TNT) have led to widespread, global contamination of soil and groundwater.
Sparrow, Helen
core   +4 more sources

Glutathione synthesis [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
Glutathione (GSH) is present in all mammalian tissues as the most abundant non-protein thiol that defends against oxidative stress. GSH is also a key determinant of redox signaling, vital in detoxification of xenobiotics, and regulates cell proliferation, apoptosis, immune function, and fibrogenesis.
openaire   +2 more sources

Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]

, 2002
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Schauer, R., Rolf Schauer, Andreas Baron, Christian Steib, Ebensberger, S., Stefan Ebensberger, Manfred Bilzer, Steib, C., Alexander L. Gerbes, Baron, A., Bilzer, M., Gerbes, Alexander L.   +11 more
core   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source

Lung uptake of two SPECT markers identifies sensitivity to hyperoxia-induced acute respiratory distress syndrome in rats

Frontiers in Physiology
IntroductionExposure of adult rats to hyperoxia is a well-established model of human Acute Respiratory Distress Syndrome (ARDS). Although rats exposed to 100% O2 display clinical evidence of lung injury after ∼40 h and death by 72 h, rats exposed to 60 ...
Anne V. Clough, Anne V. Clough, Anne V. Clough, Pardis Taheri, Pardis Taheri, Guru P. Sharma, Ming Zhao, Elizabeth R. Jacobs, Said H. Audi, Said H. Audi, Said H. Audi   +10 more
doaj   +1 more source

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Journal of Ayurveda and Integrative Medicine, 2010
Triphala (TP) is composed of Emblica officinalis, Terminalia chebula, and Terminalia belerica. The present study was undertaken to evaluate its anticataract potential in vitro and in vivo in a selenite-induced experimental model of cataract.
Suresh Kumar Gupta, V Kalaiselvan, Sushma Srivastava, Shyam S Agrawal, Rohit Saxena   +4 more
doaj   +1 more source