Journal of Biological Chemistry, 1982 The intracellular glutathione redox state was estimated using newly adapted methods for tissue analysis. Under standard perfusion conditions of rat liver perfused in situ, intracellular GSH content was 5.5 mumol X g of liver-1, and intracellular GSSG content was 18 nmol X g of liver-1, resulting in a GSH/GSSG ratio of 300. GSSG was transported from the
Theodorus P.M. Akerboom +2 more
openaire +4 more sources
MicroRNA-362-5p promotes the proliferation and inhibits apoptosis of trophoblast cells via targeting glutathione-disulfide reductase. [PDF]
Bioengineered, 2021 Zhang C, Zhao D.
europepmc +3 more sources
Glutathione Disulfide as a Reducing, Capping, and Mass-Separating Agent for the Synthesis and Enrichment of Gold Nanoclusters. [PDF]
Nanomaterials (Basel), 2021 Water-soluble nanoclusters, which are facilely enrichable without changes in the original properties, are highly demanded in many disciplines. In this contribution, a new class of gold nanoclusters (AuNCs) was synthesized using glutathione disulfide ...
Zhang Q +7 more
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Reduced glutathione and glutathione disulfide in the blood of glucose-6-phosphate dehydrogenase-deficient newborns. [PDF]
BMC Pediatr, 2017 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is commonly detected during mass screening for neonatal disease. We developed a method to measure reduced glutathione (GSH) and glutathione disulfide (GSSG) using tandem mass spectrometry (MS/
Gong ZH +4 more
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The Eye Lens Protein, γS Crystallin, Undergoes Glutathionylation-Induced Disulfide Bonding Between Cysteines 22 and 26. [PDF]
BiomoleculesThe oxidation of cysteines in crystallins is a major age-related modification associated with cataract formation. The purpose of this research was to determine the susceptibility of γS-crystallin to glutathionylation-induced oxidation and disulfide bond ...
Halverson-Kolkind K +5 more
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Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS. [PDF]
Metabolites, 2020 Glutathione (GSH) and glutathione disulfide (GSSG) are commonly used to assess the oxidative status of a biological system. Various protocols are available for the analysis of GSH and GSSG in biomedical specimens.
Sun X +7 more
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The ABC transporter Opp imports reduced glutathione, while Gsi imports glutathione disulfide in Escherichia coli. [PDF]
Redox BiolGlutathione is the major thiol-based antioxidant in a wide variety of biological systems, ranging from bacteria to eukaryotes. As a redox couple, consisting of reduced glutathione (GSH) and its oxidized form, glutathione disulfide (GSSG), it is crucial ...
Knoke LR +3 more
europepmc +2 more sources
The Status of Antioxidants and Oxidative Damage in Patients with COVID-19
Ahi Evran Medical Journal, 2023 Purpose: COVID-19 is a viral disease that has recently caused a pandemic and significantly affects human health. In this study, superoxide dismutase, glutathione peroxidase, glutathione, total thiol, natural thiol, disulfide, oxidative DNA damage and ...
İrfan BİNİCİ +7 more
doaj +1 more source
Elemental Sulfur Inhibits Yeast Growth via Producing Toxic Sulfide and Causing Disulfide Stress
Antioxidants, 2022 Elemental sulfur is a common fungicide, but its inhibition mechanism is unclear. Here, we investigated the effects of elemental sulfur on the single-celled fungus Saccharomyces cerevisiae and showed that the inhibition was due to its function as a strong
Tianqi Wang +6 more
doaj +1 more source
Altered serum glutathione disulfide levels in acute relapsed schizophrenia are associated with clinical symptoms and response to electroconvulsive therapy. [PDF]
BMC PsychiatryXu L +6 more
europepmc +2 more sources