Results 271 to 280 of about 77,313 (353)

Disrupted Redox Regulation and Inflammatory Response in Pyoderma Gangrenosum. [PDF]

Life (Basel)
Georgescu SR, Matei C, Ene CD, Capusa C, Tampa M, Mitran MI, Mitran CI, Nicolae G, Nicolae I.   +8 more
europepmc   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

An Orthogonal Protection Strategy for the Synthesis of Conotoxins Containing Three Disulfide Bonds. [PDF]

Mar Drugs
Zhang H, Chan LY, Zhang H, Jiang T, Craik DJ, Cai W, Yu R.   +6 more
europepmc   +1 more source

A metastasis‐associated pannexin‐1 mutant (Panx11‐89) forms a minimalist ATP release channel

The FEBS Journal, EarlyView.
A truncation mutant of Panx1 (Panx11‐89), enriched in metastatic breast cancer cells, is capable of forming a large ATP‐permeable membrane channel despite containing only 20% of the amino‐terminal amino acids of the wild‐type channel protein (wtPanx1). However, cells expressing Panx11‐89 alone die, whereas co‐expression of wtPanx1 is protective.
Junjie Wang, Noah J. Levi, Maykelis Diaz‐Solares, Carsten Mim, Gerhard Dahl, Rene Barro‐Soria   +5 more
wiley   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

The FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser, Milena Lubisch, Emma Schröder, Luka Ressmann, Marie Nicolaus, Dustin Leusder, Sven Moyzio, Robert Peuss, Antonio Miranda‐Vizuete, Eva Liebau   +9 more
wiley   +1 more source

Protein disulfide isomerase plays a crucial role in mediating chemically-induced, glutathione depletion-associated hepatocyte injury in vitro and in vivo

Yan-Yin Zhu, Qi Zhang, Yi-Chen Jia, Ming‐Jie Hou, Bao Ting Zhu   +4 more
openalex   +1 more source

Major Oxidative and Antioxidant Mechanisms During Heat Stress-Induced Oxidative Stress in Chickens. [PDF]

Antioxidants (Basel)
Aryal B, Kwakye J, Ariyo OW, Ghareeb AFA, Milfort MC, Fuller AL, Khatiwada S, Rekaya R, Aggrey SE.   +8 more
europepmc   +1 more source

Matching maternal and paternal experiences underpin molecular thermal acclimation

Molecular Ecology, EarlyView.
Abstract The environment experienced by one generation has the potential to affect the subsequent one through non‐genetic inheritance of parental effects. Since both mothers and fathers can influence their offspring, questions arise regarding how the maternal, paternal and offspring experiences integrate into the resulting phenotype.
L. C. Bonzi, J. M. Donelson, R. K. Spinks, P. L. Munday, T. Ravasi, C. Schunter   +5 more
wiley   +1 more source

Thiamine disulfide derivatives in thiol redox regulation: Role of thioredoxin and glutathione systems

Alessandra Folda, Valeria Scalcon, Federica Tonolo, Maria Pia Rigobello, Alberto Bindoli   +4 more
openalex   +1 more source

Molecular basis for the enzymatic inactivity of class III glutaredoxin ROXY9 on standard glutathionylated substrates. [PDF]

Nat Commun
Mrozek P, Grunewald S, Treffon K, Poschmann G, Rabe von Pappenheim F, Tittmann K, Gatz C.   +6 more
europepmc   +1 more source