Results 41 to 50 of about 77,313 (353)

The Redox Potential of the β-93-Cysteine Thiol Group in Human Hemoglobin Estimated from In Vitro Oxidant Challenge Experiments

open access: yesMolecules, 2021
Glutathionyl hemoglobin is a minor form of hemoglobin with intriguing properties. The measurement of the redox potential of its reactive β-93-Cysteine is useful to improve understanding of the response of erythrocytes to transient and chronic conditions ...
Federico Maria Rubino
doaj   +1 more source

Novel Method to Process Cystic Fibrosis Sputum for Determination of Oxidative State [PDF]

open access: yes, 2010
Background: Induced sputum is the most commonly used method to analyze airway inflammation in cystic fibrosis (CF) patients ex vivo. Due to the complex matrix of the sample material, precise and reliable analysis of sputum constituents depends critically
Feilcke, M.   +5 more
core   +1 more source

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants

open access: yeseLife, 2014
Protein folding homeostasis in the endoplasmic reticulum (ER) requires efficient protein thiol oxidation, but also relies on a parallel reductive process to edit disulfides during the maturation or degradation of secreted proteins.
Satoshi Tsunoda   +7 more
doaj   +1 more source

Glutathione accelerates sodium channel inactivation in excised rat axonal membrane patches [PDF]

open access: yes, 1992
The effects of glutathione were studied on the gating behaviour of sodium channels in membrane patches of rat axons. Depolarizing pulses from –120 to –40 mV elicited sodium currents of up to 500 pA, indicating the simultaneous activation of up to 250 ...
B Neumcke   +15 more
core   +1 more source

Capillary Isotachophoresis Determination of Trace Oxidized Glutathione in Blood

open access: yesHungarian Journal of Industry and Chemistry, 2018
A capillary isotachophoresis (CITP) method performed in a column-coupling apparatus has been developed for the simultaneous determination of glutathione (GSH) and glutathione disulfide (GSSG) concentrations in blood samples. The determination of GSSG and
Bodor Robert   +3 more
doaj   +1 more source

Role of glutathionylation in infection and inflammation [PDF]

open access: yes, 2019
Glutathionylation, that is, the formation of mixed disulfides between protein cysteines and glutathione (GSH) cysteines, is a reversible post-translational modification catalyzed by dierent cellular oxidoreductases, by which the redox state of the cell
Baldelli, S.   +5 more
core   +1 more source

Pathogenic effects of plasma thiols in patients with psoriasis on background of arterial hypertension

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Objective: to study the features of metabolism of nitric oxide and thiol-disulfide balance parameters in patients with psoriasis combined with essential hypertension. Materials and metods.
G. I. Makurina
doaj   +1 more source

Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn's Disease. [PDF]

open access: yesTurk J Gastroenterol
Background/Aims: Crohn’s disease (CD) is a major subtype of chronic relapsing inflammatory gastrointestinal disorders. In this study, we assessed the possible contributions of serum oxidative/nitrosative stress and dynamic thiol/disulfide homeostasis to ...
Bağdaş AA   +3 more
europepmc   +2 more sources

Mitochondrial thiol-disulfide system under acute hypoxia and hypoxic-hyperoxic adaptation [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2014
The authors investigated the state of mitochondrial glutathione pool (reduced and oxidized glutathione, protein-GSH mixed disulfides), content of carbonyl groups and free sulfhydryl groups of proteins, protein expression of key mitochondrial antioxidant ...
O. A. Gonchar, I. N. Mankovska
doaj   +1 more source

Transport in disordered monolayer molybdenum disulfide nanoflakes: evidence for inhomogeneous charge transport [PDF]

open access: yesNanotechnol. 25, 375201 (2014), 2014
We study charge transport in a monolayer molybdenum disulfide nanoflake over a wide range of carrier density, temperature, and electric bias. We find that the transport is best described by a percolating picture in which the disorder breaks translational invariance, breaking the system up into a series of puddles, rather than previous pictures in which
arxiv   +1 more source

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