Results 121 to 130 of about 122,606 (315)

Serum antioxidants as predictors of the adult respiratory distress syndrome in septic patients [PDF]

, 1993
Adult respiratory distress syndrome (ARDS) can develop as a complication of various disorders, including sepsis, but it has not been possible to identify which of the patients at risk will develop this serious disorder.
Beutler, Brown, Buhl, C.E. Day, Carvalho, Cejka, Duswald, Dwenger, E.E. Moore, F.A. Moore, H. Fritz, Hilgenfeldt, J.A. Leff, J.E. Repine, J.M. McCord, Kawaguchi, Leff, Leff, Leff, M. Jochum, N. Taniguchi, P.E. Parsons, Pacht, Parsons, Repine, Rocker, Rubin, Suter, Taniguchi, White, Wong   +30 more
core   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA

Cancer Communications, Volume 42, Issue 12, Page 1347-1366, December 2022., 2022
Abstract Background N‐acetyltransferase 10 (NAT10) is the only enzyme known to mediate the N4‐acetylcytidine (ac4C) modification of mRNA and is crucial for mRNA stability and translation efficiency. However, its role in cancer development and prognosis has not yet been explored.
Xiao Zheng, Qi Wang, You Zhou, Dachuan Zhang, Yiting Geng, Wenwei Hu, Changping Wu, Yufang Shi, Jingting Jiang   +8 more
wiley   +1 more source

Erectile dysfunction drugs and oxidative stress in the liver of male rats

Toxicology Reports, 2015
Erectile dysfunction (ED) affected the lives of more than 300 million men worldwide. Erectile dysfunction drugs (EDD), known as phosphodiesterase inhibitors (PDEIs), have been used for treatment of ED.
Salah Sheweita, Basant Salama, Mostafa Hassan   +2 more
doaj   +1 more source

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

Advanced Science, EarlyView.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen, Dongwei Liu, Lei Lei, Ting Liu, Shaokang Pan, Hui Wang, Yong Liu, Yingjin Qiao, Zhangsuo Liu, Qi Feng   +9 more
wiley   +1 more source

Robust Retrospective Frequency and Phase Correction for Single-voxel MR Spectroscopy [PDF]

arXiv, 2018
Purpose: subject motion and static field (B$_0$) drift are known to reduce the quality of single voxel MR spectroscopy data due to incoherent averaging. Retrospective correction has previously been shown to improve data quality by adjusting the phase and frequency offset of each average to match a reference spectrum.
arxiv  

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

Advanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu, Xing‐Yue Zhou, Da‐Lian Qin, Qan Qiao, Qiao‐Zhi Wang, Shi‐Ying Li, Yun‐Fei Zhu, Ya‐Ping Li, Jiang‐Min Zhou, Hui Cai, Fei‐Hong Huang, Lu Yu, Long Wang, An‐Guo Wu, Jian‐Ming Wu, Xiao‐Gang Zhou   +15 more
wiley   +1 more source

Antioxidant Effects of Some Drugs on Ethanol-induced Ulcers

Molecules, 2009
The aim of this work was to investigate the antioxidant potential of some commonly used drugs (bromocriptine, haloperidol and azithromycin) on alcohol-induced ulcers in the rat.
Svetlana Trivic, Julijana Rasic, Biljana Kaurinovic, Snezana Janicijevic-Hudomal, Mira Popovic   +4 more
doaj   +1 more source

Pt nanoparticles dispersed in a metal-organic framework as peroxidase mimics for colorimetric detection of GSH [PDF]

arXiv
Metal-organic skeleton materials have been widely used in catalysis with their porous structure and adsorption properties. Precious metal nanoparticles have good catalytic properties. If the noble metal nanoparticles are adsorbed on the MOFs surface, the active sites can be increased and the catalytic effect of the materials can be greatly improved. We
arxiv  

Azadirachta indica induced suppression of Mycobacterium tuberculosis secreted proteins in human monocyte [PDF]

, 2008
The H37Rv strain of MTB was grown in modified Sauton’s medium till mid-log phase. Peripheral blood mononuclear cells (PBMC) were isolated by density gradient sedimentation on Ficoll-Paque separation medium.
Ajay Kumar, Jawed Iqbal, Najmul Islam
core   +2 more sources