Results 201 to 210 of about 240,067 (266)

Synergistic Intra‐ and Inter‐Nanozyme Electron Transfer through Interfacial Assembly for Enhanced Multi‐Enzyme Activity

Advanced Science, EarlyView.
A novel Prussian blue‐based composite nanoenzymes (PB C‐NZs)‐MoS2/PB, was designed based on the electron transfer mechanism and transport pathway. The structure uses MoS2 as the substrate, with PB grown on its surface through a surface assembly method.
Kun Lu, Jizi Liu, Xiaoyang Zhu, Yu Mao, Hongliang He, Pingqiang Cai, Yan Li, Ning Gu   +7 more
wiley   +1 more source

PR/SET domain 1 targeting glutathione peroxidase 4 regulates chronic hepatitis B liver fibrosis through ferroptosis. [PDF]

Cytojournal
Wu W, Ke W, Shi W, Lin T, Lin S, Lin M, Ma H, Gao H.   +7 more
europepmc   +1 more source

Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization. [PDF]

Int J Mol Sci, 2022
Soria-Tiedemann M, Michel G, Urban I, Aldrovandi M, O'Donnell VB, Stehling S, Kuhn H, Borchert A.   +7 more
europepmc   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source

Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function

Angewandte Chemie, EarlyView.
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou, Ling Zhang, Zhuoyi L. Niu, Xin Wang, Alejandro Storper, Ryan Hunt, Yingming Zhao, Nima Sharifi, Zhipeng A. Wang   +8 more
wiley   +2 more sources

Simultaneous regulation of ferroptosis suppressor protein 1 and glutathione peroxidase 4 as a new therapeutic strategy of ferroptosis for esophageal squamous cell carcinoma. [PDF]

Esophagus, 2023
Miyauchi W, Shishido Y, Matsumi Y, Matsunaga T, Makinoya M, Shimizu S, Miyatani K, Sakamoto T, Umekita Y, Hasegawa T, Fujiwara Y.   +10 more
europepmc   +1 more source

4-hydroxynonenal, a lipid peroxidation product, inhibits glutathione peroxidase: Protective effect of glutathione

Pathophysiology, 1998
Francisco Bosch-Morell, Leopold Flohé, Nuria Marín, Francisco J. Romero   +3 more
openaire   +1 more source

Grape Seed Polyphenols Enhance Antioxidant Activity and Prolong the Lifespan of Caenorhabditis elegans Through SKN‐1/Nrf2 Pathway

AgriFood: Journal of Agricultural Products for Food, EarlyView.
GSP extends C. elegans lifespan, enhances stress resistance and reproduction, boosts antioxidant defenses (↑SOD/CAT/GSH‐Px, ↓ROS), remodels glycolysis/TCA/one‐carbon metabolism dose‐dependently, and activates SKN‐1/Nrf2 and H3K4 methylation—linking redox control to epigenetic modulation.
Boya Ouyang, Quanyong Wu, Fei Liu, Jingyimei Liang, Wanning Ma, Yuxuan Zhao, Hui Cao, Jianbo Xiao   +7 more
wiley   +1 more source

Inhibition of glutathione peroxidase and the effect on lipid and myoglobin oxidation in beef [PDF]

, 2012
Claeys, Erik, De Smet, Stefaan, Pastsart, Umaporn   +2 more
core  

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng, Anusha Jayaraman, Richard Reynolds, Jia Nee Foo   +3 more
wiley   +1 more source