Food Chemistry: X, 2023 The study aimed to assess differences in proteomic and metabolite profiles in ageing (1, 2, 4, and 6 days at 4 °C) beef exudates and determine their relationship with beef muscle iron metabolism and oxidation.
Jun Liu +9 more
doaj +1 more source
Antioxidant status in acute stroke patients and patients at stroke risk [PDF]
, 2004 Background and Purpose: Antioxidant enzymes like copper/ zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular ...
Haberl, R. L. +4 more
core +1 more source
A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]
, 2018 Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro +6 more
core +2 more sources
Role of Glutathione Peroxidase 4 in Conjunctival Epithelial Cells
Investigative Ophthalmology & Visual Science, 2015 The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in conjunctival epithelial cells.An immortalized human conjunctival epithelial cell line was used. Cells were transfected with catalase, GPx1, GPx4, SOD1, SOD2, or control siRNA. Knockdown was confirmed by RT-PCR and immunoblotting.
Osamu, Sakai +4 more
openaire +2 more sources
The Regulatory Effects and the Signaling Pathways of Natural Bioactive Compounds on Ferroptosis
Foods, 2021 Natural bioactive compounds abundantly presented in foods and medicinal plants have recently received a remarkable attention because of their various biological activities and minimal toxicity.
Shenshen Zhang +5 more
doaj +1 more source
Azadirachta indica induced suppression of Mycobacterium tuberculosis secreted proteins in human monocyte [PDF]
, 2008 The H37Rv strain of MTB was grown in modified Sauton’s medium till mid-log phase. Peripheral blood mononuclear cells (PBMC) were isolated by density gradient sedimentation on Ficoll-Paque separation medium.
Ajay Kumar, Jawed Iqbal, Najmul Islam
core +2 more sources
Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries
Antioxidants, 2023 Ferroptosis is involved in various tissue injuries including neurodegeneration, ischemia-reperfusion injury, and acute liver injury. Ferroptosis inhibitors exhibit promising clinical potential in the treatment of various diseases.
Wentao Duan +11 more
doaj +1 more source
Is there an interplay between adherence to mediterranean diet, antioxidant status, and vascular disease in atrial fibrillation patients? [PDF]
, 2015 Mediterranean Diet (Med-Diet) is associated with reduced incidence of vascular events (VEs) in atrial fibrillation (AF), but the mechanism accounting for its beneficial effect is only partially known.
PASTORI, DANIELE +8 more
core +4 more sources
Ferrostatin-1 protects HT-22 cells from oxidative toxicity
Neural Regeneration Research, 2020 Ferroptosis is a type of programmed cell death dependent on iron. It is different from other forms of cell death such as apoptosis, classic necrosis and autophagy. Ferroptosis is involved in many neurodegenerative diseases.
Jun Chu +3 more
doaj +1 more source
Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells [PDF]
, 2014 It is known that fluoride produces oxidative stress. Inflammation in bone tissue and an impairment of the respiratory chain of liver have been described in treatments with fluoride. Whether the impairment of the respiratory chain and oxidative stress are
Fina, Brenda +3 more
core +1 more source