Results 201 to 210 of about 21,313 (286)

Histone acetyltransferase KAT6A contributes to colon cancer malignant progression by inhibiting ferroptosis. [PDF]

BMC Cancer
Huo J, Chen H, Zhang X, Sun D, Sheng H, Jiang Y.   +5 more
europepmc   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Programmed Activatable Photosensitizer for Acidity/Glutathione Dual‐Locked Photodynamic Theranostics of Tumors

Aggregate, Volume 7, Issue 3, March 2026.
A programmed activatable long‐wavelength photosensitizer (LET‐19) integrated an oxazinane moiety and 3,5‐bis(trifluoromethyl)benzenethiol group into the iodinated cyanine skeleton was developed for acidity/glutathione dual‐locked photodynamic theranostics of tumors.
Chao Zhao, Xinlan Lai, Yu Zhang, Shan Lei, Yurong Liu, Peng Huang, Jing Lin   +6 more
wiley   +1 more source

Combining network pharmacology and experimental validation to demonstrate that salidroside alleviates acute lung injury by inhibiting ferroptosis via the MAPK/GPX4 pathway. [PDF]

Respir Res
Zhao M, Fang W, Chen M, Wang MQ, Lin W.
europepmc   +1 more source

Cell Membrane‐Camouflaged Gold Nanoclusters/Nanoflowers for Synergistic Ferroptosis‐Like and Photothermal Therapy of Breast Cancer

Aggregate, Volume 7, Issue 3, March 2026.
Coated with cell membrane, CM‐NC@NF evades immune clearance, accumulates via EPR effect, and upon laser irradiation, generates ROS to induce ferroptosis‐like deth and photothermal therapy, enhancing cancer cell death. ABSTRACT Gold nanocluster (NC)‐induced ferroptosis has emerged as a promising method for malignant tumors. However, the immune clearance
Qixuan Wang, Shu Lian, Wenfei Niu, Zhongming Ye, Lejing Hu, Lu Huang, Yanjie Zhang, Xiaodong Xie, Jianping Xie   +8 more
wiley   +1 more source

The Berberine Derivative BBR684 Inhibits VDAC Oligomerization to Suppress Ferroptosis in Acute Kidney Injury. [PDF]

Curr Ther Res Clin Exp
Jiang Z, Zhang W, Zhu J, Wang C, Chen G, Guo Y.   +5 more
europepmc   +1 more source

Clinicopathological and prognostic significance of GPX2 protein expression in esophageal squamous cell carcinoma [PDF]

, 2016

core   +1 more source

c‐MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis‐Associated Encephalopathy

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
c‐MAF and its downstream target Slc40a1 were identified as key regulators of ferroptosis in septic mouse hippocampi. Neuron‐specific knockdown of either gene aggravated CLP‐induced cognitive deficits and ferroptosis, whereas their overexpression exerted protective effects.
Wenqin Song, Qianni Shen, Hui Zhang, Xueshan Bu, Wenwei Gao, Wei Wang   +5 more
wiley   +1 more source

Kaempferol Attenuates Oxidative Stress-Induced Injury in Gastric Mucosal Cells by Activating Nrf2/GPX4 Axis to Inhibit Ferroptosis. [PDF]

Immun Inflamm Dis
Luo C, Yan J, Shen Y, Sun Z, Xiao X.
europepmc   +1 more source