Results 261 to 270 of about 21,313 (286)

Dissecting the role of selenothiol- versus thiol-based catalysis using the model enzyme glutathione peroxidase 4 (GPx4)

2014
Bei Selenocystein (Sec) handelt es sich um die 21igste Aminosäure. Im Gegensatz zu anderen Aminosäuren ist der Einbau von Selenocystein in die entstehende Polypeptidkette sehr viel komplexer, da Sec von dem Opal Stopcodon UGA codiert wird. Eine komplexe und hochentwickelte Maschinerie ist erforderlich um den korrekten, ko-translationalen Einbau von Sec
openaire   +2 more sources

Glutathione peroxidase 4 (Gpx4) and ferroptosis: What's so special about it?

2015
The system XC−/glutathione/glutathione peroxidase 4 axis pivotally controls ferroptosis, a recently described form of regulated, non-apoptotic cell death. Compelling evidence established that this cell death route is of high relevance not only for triggering cancer cell death, but also proves to be amenable for therapeutic intervention to halt ...
Conrad, M., Friedmann Angeli, J.P.F.
openaire   +1 more source

Glutathion peroxidase 4 (GPX4) and Ribosomal Protein L40 (RPL40) participate in arsenic induced progression of renal cell carcinoma by regulating the NLRP3 mediated classic pyroptosis pathway

International Journal of Biological Macromolecules
Epidemiological studies have demonstrated that long-term exposure to high‑arsenic water increases the risk of kidney cancer. Kidney dysfunction can lead to the accumulation of metabolic waste and chronic inflammation, with the latter being a significant factor in tumor development.
Xiaodan, Zhang, Jinyu, Li, Jing, He, Yuanyuan, Li, Dianjun, Sun, Wei, Zhang   +5 more
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

The role of Glutathione Peroxidase enzyme 4 (GPX4) in human squamous cell carcinoma of the oral cavity

Journal of Cancer Diagnosis, 2018
Masakatsu Fukuda, Hideaki Sakashita
openaire   +1 more source

Glutathion Peroxidase 4 (Gpx4)

2015
openaire   +1 more source

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa, Joyce M Slingerland   +1 more
exaly  

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg, William L Hwang, Anirban Maitra   +2 more
exaly  

Oral complications of cancer and cancer therapy

Ca-A Cancer Journal for Clinicians, 2012
Joel B Epstein, Rene-Jean Bensadoun, Andrei Barasch   +2 more
exaly  

The financial burden and distress of patients with cancer: Understanding and stepping‐up action on the financial toxicity of cancer treatment

Ca-A Cancer Journal for Clinicians, 2018
Pricivel M Carrera, Hagop M Kantarjian, Victoria S Blinder   +2 more
exaly