NOX-like ROS production by glutathione reductase [PDF]
iScience, 2022 Summary: In organisms from bacteria to mammals, NADPH oxidase (NOX) catalyzes the production of beneficial reactive oxygen species (ROS) such as superoxide (O2−).
Julia M. Diaz, Xinying Shi
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Characterization and enzymatic function of thioredoxin glutathione reductase in Orientobilharzia turkestanicum isolated from Xizang [PDF]
BMC Veterinary ResearchOrientobilharziasis, caused by Orientobilharzia turkestanicum, is a zoonotic parasitic disease that leads to significant economic losses in livestock and cercarial dermatitis in humans.
Wenqiang Tang +4 more
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Evaluation of the salivary level of glutathione reductase, catalase and free thiol in patients with oral lichen planus [PDF]
BMC Oral Health, 2023 Objective Oral lichen planus (OLP) is a usual chronic inflammatory disease of the oral mucosa with malignant capacity, whose pathogenesis is not yet well known.
Fahimeh Rezazadeh +5 more
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Glutathione Reductase Is Inhibited by Acetaminophen-glutathione Conjugate In Vitro
Physiological Research, 2010 The aim of the present work was to investigate a new mechanism likely contributing to the toxic action of acetaminophen, especially to explore the possible inhibition of glutathione reductase through an acetaminophen-glutathione conjugate (APAP-SG). APAP-SG conjugate was synthesized by organic synthesis and purified by column chromatography.
Pařík, Patrik +4 more
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Cell Reports, 2017 Energetic nutrients are oxidized to sustain high intracellular NADPH/NADP+ ratios. NADPH-dependent reduction of thioredoxin-1 (Trx1) disulfide and glutathione disulfide by thioredoxin reductase-1 (TrxR1) and glutathione reductase (Gsr), respectively ...
Arne Holmgren +2 more
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The assessment of glutathione, glutathione peroxidase, glutathione reductase, and oxidized glutathione in patients with periodontitis—A systematic review and meta‐analysis [PDF]
Clinical and Experimental Dental ResearchObjective The present systematic review explored the involvement of enzymatic and nonenzymatic antioxidants in periodontitis, drawing from established literature. Materials and Methods The research approach encompassed an extensive electronic search from
Khadijah Mohideen +5 more
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Metabolism and toxicity of two new benzodiazepine-type antileishmanial agents in hepatocytes and macrophages [PDF]
, 2007 With increasing reports of resistance of Leishmania to antimonials (Thakur et al., 2004) and other traditional antileishmanial drugs, the need for the discovery of new antileishmanial agents is rising.
Mullen, A.B. +5 more
core +4 more sources
Dynamics of glutathione reductase activity in rat liver tissues during cryodestruction of the right atrium [PDF]
E3S Web of Conferences, 2021 The metabolic processes of the human body are based on multiple redox reactions and oxidative stress occurs when homeostasis is imbalanced.
Pavlova Olga +4 more
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Establishing reference intervals for serum glutathione reductase in healthy adults. [PDF]
Arch Med SciIntroduction Glutathione reductase (GR) is a key enzyme that catalyzes the reduction of oxidized glutathione to its reduced form, playing a vital role in protecting cells from oxidative damage caused by the accumulation of reactive oxygen species.
Liu Q +6 more
europepmc +2 more sources
Long-term results of the enzyme glutation system activity in experimental ovarian cancer
Journal of Education, Health and Sport, 2022 The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova +4 more
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