Results 31 to 40 of about 161,743 (309)

Effect of ochratoxin A and buthionine sulfoximine on proteome and ascorbate-glutathione cycle enzymes in Arabidopsis thaliana

Biologia Plantarum, 2015
In this study, proteome and activities of glutathione (GSH)-related enzymes were investigated in detached leaves of Arabidopsis thaliana treated with ochratoxin A (OTA) alone or supplemented with buthionine sulfoximine (BSO, a specific inhibitor of the ...
J. R. Hao, Y. Wang, W. W. Zhao, W. T. Xu, Y. B. Luo, Z. J. Yang, W. H. Wu, Z. H. Liang, K. L. Huang   +8 more
doaj   +1 more source

Remote ischemic conditioning improves rat brain antioxidant defense in a time-dependent mechanism

Acta Cirúrgica Brasileira, 2021
Purpose To clarify the best protocol for performing remote ischemic conditioning and to minimize the consequences of ischemia and reperfusion syndrome in brain, the present study aimed to evaluate different time protocols and the relation of the organs ...
Andrew Moraes Monteiro, Rodrigo Paracampo Couteiro, Dora Fonseca da Silva, Sérgio Cunha Trindade Júnior, Renata Cunha Silva, Luís Fernando Freitas de Sousa, Deivid Ramos dos Santos, Jofre Jacob da Silva Freitas, Marcus Vinícius Henriques Brito   +8 more
doaj   +1 more source

Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. [PDF]

, 2016
The reduction of oxidative stress is suggested to be one of the main mechanisms to explain the benefits of subnormothermic perfusion against ischemic liver damage. In this study we investigated the early cellular mechanisms induced in isolated rat livers
Alva, Norma, Carbonell, Teresa, Dewey, Shannamar, Gomes, Aldrin V, Sanchez-Nuño, Sergio   +4 more
core   +4 more sources

Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice

Redox Biology, 2016
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea.
Ruixia Dong, Dongxu Wang, Xiaoxiao Wang, Ke Zhang, Pingping Chen, Chung S. Yang, Jinsong Zhang   +6 more
doaj   +1 more source

Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles: a combined targeted and proteomic approach [PDF]

, 2014
Two different zinc oxide nanoparticles, as well as zinc ions, are used to study the cellular responses of the RAW 264 macrophage cell line. A proteomic screen is used to provide a wide view of the molecular effects of zinc, and the most prominent results
Armand, Lucie, Aude-Garcia, Catherine, Carrière, Marie, Collin-Faure, Véronique, Diemer, Hélène, Gerdil, Adèle, Habert, Aurélie, Hanau, Daniel, Herlin, Nathalie, Proamer, Fabienne, Rabilloud, Thierry, Strub, Jean-Marc, Triboulet, Sarah, Van Dorsselaer, Alain   +13 more
core   +4 more sources

Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania spp. against nitrosothiol-induced cytotoxicity

Brazilian Journal of Medical and Biological Research, 2006
Glutathione is the major intracellular antioxidant thiol protecting mammalian cells against oxidative stress induced by oxygen- and nitrogen-derived reactive species.
P.R.T. Romão, J. Tovar, S.G. Fonseca, R.H. Moraes, A.K. Cruz, J.S. Hothersall, A.A. Noronha-Dutra, S.H. Ferreira, F.Q. Cunha   +8 more
doaj   +1 more source

Praseodymium enhanced the tolerance of maize seedlings subjected to cadmium stress by up-regulating the enzymes in the regeneration and biosynthetic pathways of ascorbate and glutathione

Plant, Soil and Environment, 2021
To test whether praseodymium (Pr) regulates cadmium (Cd) tolerance, we explored the effects of Pr on enzymatic activities in the regeneration and biosynthetic pathways of ascorbate and glutathione in maize seedlings under Cd stress.
Qidi Zhu, Yanyan Li, Shang Gao, Changjuan Shan   +3 more
doaj   +1 more source

Novel biosensors reveal a shift in the redox paradigm from oxidative to reductive stress in heart disease [PDF]

, 2016
No abstract ...
Anagnostopoulou, Aikaterini, De Lucca Camargo, Livia, Montezano, Augusto, Touyz, Rhian   +3 more
core   +1 more source

The Effect of an Aqueous Extract of Teucrium polium on Glutathione Homeostasis In Vitro: A Possible Mechanism of Its Hepatoprotectant Action

Advances in Pharmacological Sciences, 2010
Background. Teucrium polium is used in Arab traditional medicine to treat liver diseases. Glutathione is an important intracellular antioxidant, and intrahepatic glutathione levels are depleted in liver diseases. Hypothesis and Aim.
Stella Shtukmaster, Predrag Ljubuncic, Arieh Bomzon   +2 more
doaj   +1 more source

Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells [PDF]

, 2014
It is known that fluoride produces oxidative stress. Inflammation in bone tissue and an impairment of the respiratory chain of liver have been described in treatments with fluoride. Whether the impairment of the respiratory chain and oxidative stress are
Fina, Brenda, Lombarte, Mercedes, Rigalli, Alfredo, Rigalli, Alfredo   +3 more
core   +1 more source