Results 31 to 40 of about 89,116 (163)

Protective Effect of Wild Ginseng Extract against y-BHP-induced Oxidative Damage in HepG2 Cells Using DNA Chip

Journal of Pharmacopuncture, 2007
Objectives : This study was carried out to examine protective effect of wild ginseng extract on HepG2 human hepatoma cell line against tert-Butyl hydroperoxide (t-BHP)-induced oxidative damage.
Hyung-Seok Kim, Hee-Soo Park, Ki-Rok Kwon   +2 more
doaj   +1 more source

Glutathione cycle in diquat neurotoxicity: Assessed by intrastriatal pre-treatment with glutathione reductase [PDF]

Acta Veterinaria, 2013
Diquat (DQ) neurotoxicity mechanisms are unknown, although, it's systemic toxicity is mediated by free radical reactions. The role of glutathione cycle was assessed by glutathione reductase (GR) applied in the pre-treatment of DQ poisoning.
Đurđević Dragan, Đukić Mirjana, Ninković Milica, Stevanović Ivana, Jovanović Marina, Vasić Una   +5 more
doaj   +1 more source

Glutathione reductase activity with an oxidized methylated glutathione analog

Journal of Enzyme Inhibition and Medicinal Chemistry, 2013
The activity of glutathione reductase with an unnatural analog of oxidized glutathione was explored. The analog, L-γ-glutamyl-2-methyl-L-cysteinyl-glycine disulfide, places an additional methyl group on the alpha position of each of the central cysteine residues, which significantly increases steric bulk near the disulfide bond.
Kedrowski, Brant L., Gutow, Jonathan H., Stock, Gorman, Smith, Maureen, Jordan, Chondrea, Masterson, Douglas S.   +5 more
openaire   +2 more sources

Effects of lanthanum on the antioxidant capacity of chloroplasts and chlorophyll fluorescence parameters of maize seedlings under chromium stress

Photosynthetica, 2019
Effects of lanthanum chloride (LaCl3) on chromium tolerance of maize were investigated at chloroplast level. The results showed that Cr stress significantly increased activities of ascorbate peroxidase, glutathione reductase, monodehydro-ascorbate ...
H. DAI, C. SHAN
doaj   +1 more source

Glutathione Reductase Is Inhibited by Acetaminophen-glutathione Conjugate In Vitro

Physiological Research, 2010
The aim of the present work was to investigate a new mechanism likely contributing to the toxic action of acetaminophen, especially to explore the possible inhibition of glutathione reductase through an acetaminophen-glutathione conjugate (APAP-SG). APAP-SG conjugate was synthesized by organic synthesis and purified by column chromatography.
Pařík, Patrik, Roušar, Tomáš, Kučera, Otto, Bartoš, Martin, Červinková, Zuzana   +4 more
openaire   +3 more sources

Nitric oxide is involved in the regulation of ascorbate and glutathione metabolism in Agropyron cristatum leaves under water stress

Biologia Plantarum, 2012
This study investigated the regulation of ascorbate and glutathione metabolism by nitric oxide in Agropyron cristatum leaves under water stress. The activities of ascorbate peroxidase (APX), glutathione reductase (GR), monodehydroascorbate reductase ...
C. Shan, F. He, G. Xu, R. Han, Z. Liang
doaj   +1 more source

Increased Glutathione Reductase Expression and Activity in Colorectal Cancer Tissue Samples: An Investigational Study in Mashhad, Iran

Middle East Journal of Cancer, 2018
Background: Glutathione reductase is an important enzyme in oxidative metabolism that provides reduced glutathione from its oxidized form in the cells.
Shima Lorestani, Seyyed Isaac Hashemy, Majid Mojarad, Mohammad Keyvanloo Shahrestanaki, Ali Bahari, Mahdi Asadi, Farnaz Zahedi Avval   +6 more
doaj  

Antioxidant status in women with uterine leiomyoma: relation with sex hormones

Anais da Academia Brasileira de Ciências, 2015
Uterine leiomyomas are benign soft-tissues tumors that arise from uterine smooth muscle tissue. Etiopathogenesis of leiomyomas is not well understood. We aimed to examine whether antioxidant enzyme activities and lipid hydroperoxides level in patients ...
SNEŽANA PEJIĆ, ANA TODOROVIĆ, VESNA STOJILJKOVIĆ, LJUBICA GAVRILOVIĆ, NATAŠA POPOVIĆ, SNEŽANA B. PAJOVIĆ   +5 more
doaj   +1 more source

Red Cell Glutathione and Glutathione Reductase in Cystic Fibrosis

Experimental Biology and Medicine, 1973
SummaryRed blood cell glutathione reductase and whole blood total (oxidized and reduced) glutathione were assayed in cystic fibrosis subjects and non-cystic fibrosis controls.
B L, Shapiro, Q T, Smith, W J, Warwick
openaire   +2 more sources

Effects of lanthanum on the ascorbate and glutathione metabolism of Vigna radiata seedlings under salt stress

Biologia Plantarum, 2014
In order to elucidate the role of lanthanum (La) in response of Vigna radiata to a salt stress, we investigated the effects of La on the ascorbate and glutathione metabolism.
C. Shan, X. Zhao
doaj   +1 more source