Results 81 to 90 of about 161,743 (309)

Stabilizing quercetin and lipoate effect on enzymatic antioxidant system (glutathione peroxidase and glutathione reductase) in the retina during experimental diabetes treatment

open access: yesJournal of Ophthalmology, 2015
Introduction. The thesis actuality consists in studying the quercetin and lipoate effect during experimental diabetes treatment. Objective. To study the quercetin and lipoate effect on the antioxidant system enzymes, particularly, glutathione ...
O. A. Moroz
doaj   +1 more source

Glutathione-Mediated Neuroprotection Against Methylmercury Neurotoxicity in Cortical Culture is Dependent on MRP1 [PDF]

open access: yes, 2012
Methylmercury (MeHg) exposure at high concentrations poses significant neurotoxic threat to humans worldwide. The present study investigated the mechanisms of glutathione-mediated attenuation of MeHg neurotoxicity in primary cortical culture. MeHg (5 μM)
Liu, Xiaoqian   +4 more
core   +1 more source

Microarray analysis of spring barley cultivars displaying differing sensitivity to physiological leaf spot (PLS) [PDF]

open access: yes, 2015
peer-reviewedPhysiological leaf spot (PLS) is a disorder of spring barley (Hordeum vulgare L.), which has become more pronounced in recent years. The initial symptoms are small chlorotic/brown spots on the upper four leaves, which may develop into ...
Burke, James I.   +2 more
core   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

Role of Alpha Lipoic Acid in Oxidant /Antioxidant Status and Gene Expression of Glutathione Reductase in Hydrogen Peroxide Exposed Rats: (Part -2)

open access: yesThe Iraqi Journal of Veterinary Medicine, 2019
This study was designated to evaluate the protective role of alpha lipoic acid against oxidative stress resulted by hydrogen peroxide on some oxidants/ antioxidants  parameters and gene expression of glutathione peroxidase in  adult Wistar rats.
Baraa Najim Al-Okialy
doaj   +1 more source

Protection against photooxidative injury of tobacco leaves by 2-alkenal reductase: detoxication of lipid peroxide-derived reactive carbonyls [PDF]

open access: yes, 2005
Degradation of lipid peroxides leads to the formation of cytotoxic 2-alkenals and oxenes (collectively designated reactive carbonyls). The novel NADPH-dependent oxidoreductase 2-alkenal reductase (AER; EC 1.3.1.74) from Arabidopsis (Arabidopsis thaliana),
Mano, Jun'ichi   +9 more
core   +2 more sources

Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]

open access: yes, 2020
An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris   +9 more
core   +2 more sources

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

open access: yesAdvanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao   +10 more
wiley   +1 more source

Genetic regulation of glucoraphanin accumulation in Beneforté® broccoli [PDF]

open access: yes, 2013
Diets rich in broccoli (Brassica oleracea var italica) have been associated with maintenance of cardiovascular health and reduction in risk of cancer. These health benefits have been attributed to glucoraphanin that specifically accumulates in broccoli ...
Anon   +17 more
core   +1 more source

GLUTATHIONE DETERMINATION AND A STUDY OF THE ACTIVITY OF GLUTATHIONE-PEROXIDASE, GLUTATHIONE-TRANSFERASE, AND GLUTATHIONE-REDUCTASE IN RENAL TRANSPLANTS [PDF]

open access: yesRenal Failure, 2002
The aim of this work is to study the temporary variation of oxidative stress in renal transplants, both in plasma and in erythrocytes (CR). In order to do so, we determined total glutathione (GST) levels, both oxidized (GSSG) and reduced (GSH), and the activity of enzymes, glutathione peroxidase (G-px), glutathione reductase (G-red) and glutathione ...
Vega, L. de   +5 more
openaire   +3 more sources

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