Results 71 to 80 of about 311,263 (293)

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Balance of glutathione system activity in ascitic ovarian tumor under the experimental conditions

open access: yesJournal of Education, Health and Sport
The article presents the experimental results of the investigation the glutathione system activity in rats simulated ovarian ascites tumor. It was found that the glutathione system in the form of glutathione reductase and glutathione peroxidase is ...
V. Sarakhan
doaj   +1 more source

Glutathione Reductase Deficiency in Saudi Arabia

open access: yesAnnals of Saudi Medicine, 1989
Glutathione reductase [GR]is a ubiquitous enzyme required for the conversion of oxidized glutathione [GSSG] to reduced glutathione [GSH] concomitantly oxidizing reduced nicotinamide adenine dinucleotide phosphate [NADPH]in a reaction essential for the stability and integrity of red cells.
A S, Warsy, M A, el-Hazmi
openaire   +2 more sources

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2017
Neuronal degeneration in multiple sclerosis has been linked to oxidative stress. Dimethyl fumarate (DMF) is an effective oral therapeutic option shown to reduce disease activity and progression in patients with relapsing‐remitting multiple sclerosis. DMF activates the transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) leading to ...
Christina Hoffmann   +5 more
openaire   +3 more sources

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Stabilizing quercetin and lipoate effect on enzymatic antioxidant system (glutathione peroxidase and glutathione reductase) in the retina during experimental diabetes treatment

open access: yesJournal of Ophthalmology, 2015
Introduction. The thesis actuality consists in studying the quercetin and lipoate effect during experimental diabetes treatment. Objective. To study the quercetin and lipoate effect on the antioxidant system enzymes, particularly, glutathione ...
O. A. Moroz
doaj   +1 more source

Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation [PDF]

open access: yes, 2010
During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
core  

Photoinhibition of photosystem II in tobacco plants overexpressing glutathione reductase and poplars overexpressing superoxide dismutase

open access: yes, 1999
We studied photoinhibition in two cultivars of tobacco (Nicotiana tabacum L,) expressing the bacterial gor gene In the cytosol and in four lines of poplar (Populus tremula x P, alba) expressing the FeSOD gene of Arabidopsis thaliana in the chloroplast ...
Jouanin, L.   +5 more
core   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

Role of Alpha Lipoic Acid in Oxidant /Antioxidant Status and Gene Expression of Glutathione Reductase in Hydrogen Peroxide Exposed Rats: (Part -2)

open access: yesThe Iraqi Journal of Veterinary Medicine, 2019
This study was designated to evaluate the protective role of alpha lipoic acid against oxidative stress resulted by hydrogen peroxide on some oxidants/ antioxidants  parameters and gene expression of glutathione peroxidase in  adult Wistar rats.
Baraa Najim Al-Okialy
doaj   +1 more source

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