Results 31 to 40 of about 3,740 (48)

Glutathione S-Transferase Mu 1 and Glutathione S-transferase theta 1 Genes Polymorphism and Susceptibility to Chronic Myeloid Leukemia in Erbil-Iraq Kurdistan Region

Zanco Journal of Pure and Applied Sciences, 2020
Chronic myeloid leukemia (CML) result from many reactions of heredity non-heredity factors. The null genotype for glutathione S-transferase (GSTM1 or GSTT1) is regarded a risk agent leukemia, especially on CML in various inhabitants.
Mukhlis H. Aali, Govand Musa Qader, Mustafa S. Al-Attar, Mustafa F. Rajab, Mudhir S. Shehka   +4 more
doaj   +3 more sources

Enzymes Involved in Antioxidant and Detoxification Processes Present Changes in the Expression Levels of Their Coding Genes under the Stress Caused by the Presence of Antimony in Tomato

Plants
Currently, there is an increasing presence of heavy metals and metalloids in soils and water due to anthropogenic activities. However, the biggest problem caused by this increase is the difficulty in recycling these elements and their high permanence in ...
Francisco Luis Espinosa-Vellarino, Inmaculada Garrido, Ilda Casimiro, Ana Cláudia Silva, Francisco Espinosa, Alfonso Ortega   +5 more
doaj   +1 more source

Metabolism of hydroperoxy-phospholipids in human hepatoma HepG2 cells

Journal of Lipid Research, 1996
Two enzymatic mechanisms have been proposed for the metabolism of hydroperoxy-phospholipids: i) the combined action of phospholipase A2 and glutathione peroxidase, and/or ii) direct enzymatic reduction.
Y Bao, G Williamson
doaj  

Intoxication syndrome in patients with pulmonary tuberculosis in relation to the system glutathione transferase gene polymorphism

Журнал инфектологии, 2017
In 178 patients with different clinical forms of pulmonary tuberculosis carried out pharmacogenetic testing to determine gene polymorphism glutathione S-transferase system (GSTM1, GSTT1).
N. A. Stepanova, Kh. M. Galimzyanov, B. I. Kantemirova   +2 more
doaj   +1 more source

Glutathione S transferase polymorphisms influence on iron overload in β-thalassemia patients

Thalassemia Reports, 2013
In patients with β-thalassemia iron overload that leads to damage to vital organs is observed. Glutathione S transferase (GST) enzymes have an antioxidant role in detoxification processes of toxic substances. This role is determined genetically.
Serena Sclafani, Giuseppina Calvaruso, Veronica Agrigento, Aurelio Maggio, Valeria Lo Nigro, Elena D’Alcamo   +5 more
doaj   +1 more source

The Value of Glutathione-S-Transferase Gene Polymorphisms (GSTM1, GSTT1) in Various Inflammatory Phenotypes of Bronchial Asthma in Children

Zdorovʹe Rebenka, 2014
The aim of research: to study the peculiarities of a heterogeneous airway inflammation in children with bronchial asthma (BA) under the deletion polymorphism of GSTM1 and GSTT1 genes. Materials and Methods.
O.K. Koloskova, L.O. Bezrukov, T.M. Bilous, O.G. Grygola, Ye.P. Ortemenka   +4 more
doaj   +1 more source

GST Enzyme Content of Wheat Landraces and Comparison with Modern Varieties

Turkish Journal of Agriculture: Food Science and Technology
The development of high-yielding modern wheat varieties to feed the growing population has had a negative impact on the production of ancestral and landrace crops. The use of modern varieties, which are very deficient in vitamins, minerals, antioxidants,
Aziz Öz, Alaettin Keçeli
doaj   +1 more source

Glutathione metabolism in Urtica dioica in response to cadmium based oxidative stress

Biologia Plantarum, 2016
To investigate the antioxidative response of glutathione metabolism in Urtica dioica L. to a cadmium induced oxidative stress, activities of glutathione reductase (GR), glutathione-S-transferase (GST), and glutathione peroxidase (GSH-Px), content of ...
L. Tarhan, B. Kavakcioglu
doaj   +1 more source

Glutathione S-conjugates as prodrugs to target drug-resistant tumors

Frontiers in Pharmacology, 2014
Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic detoxification in many species is the conjugation of activated xenobiotics to reduced glutathione (GSH) catalyzed by the glutathione-S-transferase (GST).
Emma E. Ramsay, Pierre J. Dilda
doaj   +1 more source

A relação do uso crônico de fenobarbital com áreas potencialmente pré-neoplásicas em fígado de ratos Potentially pre-neoplasics areas in rat's liver associated to chronic use of phenobarbital

Arquivos de Gastroenterologia, 2006
RACIONAL: O fenobarbital é utilizado em modelos experimentais não só por ser um importante agente promotor da carcinogênese em fígado de ratos, como também por ser não-genotóxico, órgão-específico e dose-dependente.
Helena Terezinha Hubert Silva, Antonio Atalíbio Hartmann   +1 more
doaj   +1 more source