Results 61 to 70 of about 18,229,039 (247)

Glutathione in the nervous system: Roles in neural function and health and implications for neurological disease

, 2007
The chapter, "Glutathione in the nervous system: Roles in neural function and health and implications for neurological disease" was written by the listed authors including Reyniel Cruz-Aguado (Douglas College Faculty).

core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Role of oxidative modification of proteins in the regulation and realization of cell death of blood lymphocytes under the conditions of blocking glutathione synthesis under oxidative stress

Медицинская иммунология
Lymphocytes are key cells in inflammation. The realization of inflammation accompanied by the development of oxidative stress depends on metabolic processes occurring in blood lymphocytes. Experimental studies of molecular control of the redox status and
O. L. Nosareva, E. A. Stepovaya
doaj   +1 more source

Influence of cadmium loading on glutathione system of antioxidant protection of the bullocks’bodies

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2018
It was presented the results of studies of the cadmium effect loading on the activity of the glutathione system of antioxidant protection in young cattle, namely on the activity of glutathione peroxidase, glutathione reductase, glucose-6-phosphate ...
B. V. Gutyj, D. F. Gufriy, V. Y. Binkevych, R. O. Vasiv, N. V. Demus, K. Y. Leskiv, O. M. Binkevych, O. V. Pavliv   +7 more
doaj   +1 more source

Plasmodium falciparum glutathione metabolism and growth are independent of glutathione system of host erythrocyte [PDF]

FEBS Letters, 1998
Plasmodium falciparum parasites grew normally in glutathione (GSH)‐depleted normal and G6PD‐deficient (Mediterranean variant) erythrocytes (RBC). Growth inhibition was observed only at less than approximately 6–12% residual GSH. Parasites studied separately with the Sendai virus technique synthesized GSH de novo and regenerated reduced GSH 10–20 times
AYI K, CAPPADORO M, BRANCA M, TURRINI, Francesco Michelangelo, ARESE, Paolo   +4 more
openaire   +3 more sources

Glutathione transferases in maize (zea mays) [PDF]

, 1998
The glutathione transferases (GSTs) of maize have been the most studied GSTs in plants, however much is still not known about these enzymes. In the course of the current study six GST subunits (Zm GSTs I, II and III, which have been reported previously ...
Dixon, D.P., Dixon, David Peter
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

Redox Biology, 2017
Redox signaling is important for embryogenesis, guiding pathways that govern processes crucial for embryo patterning, including cell polarization, proliferation, and apoptosis.
Karilyn E. Sant, Jason M. Hansen, Larissa M. Williams, Nancy L. Tran, Jared V. Goldstone, John J. Stegeman, Mark E. Hahn, Alicia Timme-Laragy   +7 more
doaj   +1 more source

Role of glutathione transferases in herbicide detoxification in weeds [PDF]

, 1996
Glutathione transferases (GSTs) catalyse the conjugation of the electrophilic herbicides atrazine, metolachlor, alachlor and fluorodifen with the tripeptide glutathione (GSH).
Hatton, Pamela J., Hatton, P.J.
core  

Coordinate induction of glutathione biosynthesis and glutathione-metabolizing enzymes is correlated with salt tolerance in tomato

, 2003
The acclimation of reduced glutathione (GSH) biosynthesis and GSH-utilizing enzymes to salt stress was studied in two tomato species that differ in stress tolerance. Salt increased GSH content and GSH:GSSG (oxidized glutathione) ratio in oxidative stress-
Guy Kiddle, Foyer, C. H., Christine H Foyer, Theodoulou, F. L., Tal, M., Mittova, V., Micha Volokita, Micha Guy, Volokita, M., Leonardo Gómez, Frederica L Theodoulou, Moshe Tal, Valentina Mittova, Gomez, L., Kiddle, G., Guy, M., Theodoulou, Freddie   +16 more
core   +1 more source