Results 131 to 140 of about 202,820 (240)

Characterization of Dog Glutathione Transferase P1-1, an Enzyme Relevant to Veterinary Medicine. [PDF]

Int J Mol Sci, 2021
Ismail A, Lewis E, Sjödin B, Mannervik B.   +3 more
europepmc   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a <i>Morganella morganii</i> isolate from poultry. [PDF]

Front Cell Infect Microbiol
Zhang R, Yu Y, Huang L, Chen S, Hu R, Wang X, Huang D, Song C, Lu J, Bao Q, Hu Y, Jiang P, Pan W.   +12 more
europepmc   +1 more source

Quantifying the Differences in Binding Affinity of Reduced Glutathione for Glutathione S-Transferase at pH 6.5 and 8.5 Using Isothermal Titration Calorimetry

, 2018
The binding affinity between an enzyme and its substrate is often dependent on the pH of the local environment. Knowing the pH at which reduced glutathione (GSH) binds with the highest affinity to the enzyme glutathione S-transferase (GST) is useful for ...
Gary, Ronald K., Renshaw, Clay P., Jr.
core  

Toxicological Response of the BEAS‐2B Cell After Acute Exposure at the Air–Liquid Interface to Ethylbenzene and m‐Xylene Alone and in Binary Mixtures

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzene, toluene, ethylbenzene, and xylenes (o‐, m‐, and p‐xylenes) constitute a family, named BTEX, of volatile organic compounds (VOCs) known for its toxicity. This study aimed to study the acute in vitro toxicity of ethylbenzene and m‐xylene on human bronchial epithelial cells exposed at the air–liquid interface (ALI).
Nour Jaber, Claude Emond, Fabrice Cazier, Sylvain Billet   +3 more
wiley   +1 more source

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons. [PDF]

Neural Regen Res
Kim K.
europepmc   +1 more source

Induction of Apoptosis in Cancer Cells by Glutathione Transferase Inhibitor Mediated Hydrophobic Tagging Molecules. [PDF]

ACS Med Chem Lett, 2021
Li X, Lü Z, Wang C, Li K, Xu F, Xu P, Niu Y.   +6 more
europepmc   +1 more source

Exploring the Role of T‐Cell Metabolism in Modulating Immunotherapy Efficacy for Non‐Small Cell Lung Cancer Based on Clustering

Journal of Clinical Laboratory Analysis, EarlyView.
We conducted a comprehensive investigation of the metabolic profiles of infiltrating T cells in NSCLC tumors and found metabolic heterogeneity in three T‐cell subtypes, which are associated with the prognosis of ICB therapy. We defined these metabolic clusters as response‐dependent (R) clusters and non‐response‐dependent (NR) clusters, and elucidated ...
Hongzhe Guo, Liangyu Zhang, Hu Tang, Peiwen Liu, Bin Hu, Yue Gong, Rui Hou, Ziheng Wu   +7 more
wiley   +1 more source

A dual role for glutathione transferase U7 in plant growth and protection from methyl viologen-induced oxidative stress. [PDF]

Plant Physiol, 2021
Ugalde JM, Lamig L, Herrera-Vásquez A, Fuchs P, Homagk M, Kopriva S, Müller-Schüssele SJ, Holuigue L, Meyer AJ.   +8 more
europepmc   +1 more source

Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors. [PDF]

PLoS One
Sabt A, Kitsos S, Ebaid MS, Furlan V, Pantiora PD, Tsolka M, Elkaeed EB, Hamissa MF, Angelis N, Tsitsilonis OE, Papageorgiou AC, Bren U, Labrou NE.   +12 more
europepmc   +1 more source