Monocarbonyl Curcumin Analogues as Potent Inhibitors against Human Glutathione Transferase P1-1. [PDF]
Pantiora P +9 more
europepmc +1 more source
Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
wiley +1 more source
Conservation of Glutathione Transferase mRNA and Protein Sequences Similar to Human and Horse Alpha Class GST A3-3 across Dog, Goat, and Opossum Species. [PDF]
Hubert SM +4 more
europepmc +1 more source
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto +7 more
wiley +1 more source
Gamma-glutamyl cycle in plants: a bridge connecting the environment to the plant cell? [PDF]
Ganesh K., Agrawal +3 more
core +1 more source
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1. [PDF]
Chronopoulou EG +4 more
europepmc +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
Structural and Functional Characterization of Camelus dromedarius Glutathione Transferase M1-1. [PDF]
Perperopoulou F +4 more
europepmc +1 more source
Abstract BACKGROUND Obesity is a major risk factor for cardiovascular disease, primarily due to its effects on lipid metabolism, oxidative stress, and inflammation. The aim of this study was to evaluate the effects of spirulina (SP) on cafeteria diet (CD)‐induced myocardial oxidative stress and inflammation using biochemical, histological, and in ...
Fatma Arrari +3 more
wiley +1 more source

