Results 161 to 170 of about 224,471 (305)

Insect‐resistant soybean genotypes accumulate rutin and its O‐methylated derivative narcissin, a more potent flavonol targeting Anticarsia gemmatalis digestive and detoxification enzymes and reducing larval survival

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis   +9 more
wiley   +1 more source

Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. [PDF]

open access: yesFront Mol Biosci, 2022
Sylvestre-Gonon E   +8 more
europepmc   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen   +4 more
wiley   +1 more source

Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes. [PDF]

open access: yesInt J Mol Sci, 2022
Bodourian CS   +6 more
europepmc   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng   +8 more
wiley   +1 more source

The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes. [PDF]

open access: yesMolecules, 2021
Alqarni MH   +3 more
europepmc   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Structural insights into sigma class glutathione transferase from Taenia solium: Analysis and functional implications. [PDF]

open access: yesPLoS Negl Trop Dis
Miranda-Blancas R   +9 more
europepmc   +1 more source

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