Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis +9 more
wiley +1 more source
Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. [PDF]
Sylvestre-Gonon E +8 more
europepmc +1 more source
MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen +4 more
wiley +1 more source
Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes. [PDF]
Bodourian CS +6 more
europepmc +1 more source
Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng +8 more
wiley +1 more source
The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes. [PDF]
Alqarni MH +3 more
europepmc +1 more source
Expressed sequence tag survey of gene expression in the scab mite Psoroptes ovis--allergens, proteases and free-radical scavengers [PDF]
Blaxter, M L +5 more
core +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Structural insights into sigma class glutathione transferase from Taenia solium: Analysis and functional implications. [PDF]
Miranda-Blancas R +9 more
europepmc +1 more source
The Interaction of the Flavonoid Fisetin with Human Glutathione Transferase A1-1. [PDF]
Alqarni MH +3 more
europepmc +1 more source

