Journal of Applied Toxicology, EarlyView.ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger +3 more
wiley +1 more source
Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. [PDF]
Front Mol Biosci, 2022 Sylvestre-Gonon E +8 more
europepmc +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares +6 more
wiley +1 more source
Identification and characteristics of a novel fosfomycin glutathione transferase, FosA12, from an MDR clinical isolate of <i>Proteus vulgaris</i>. [PDF]
Antimicrob Agents ChemotherLu W +7 more
europepmc +1 more source
Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes. [PDF]
Int J Mol Sci, 2022 Bodourian CS +6 more
europepmc +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol +4 more
wiley +1 more source
Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis. [PDF]
BMC MicrobiolEl-Sayed ASA +5 more
europepmc +1 more source
The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes. [PDF]
Molecules, 2021 Alqarni MH +3 more
europepmc +1 more source
Journal of the Chinese Chemical Society, EarlyView.Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian
, 2009 Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Guang Wang +6 more
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