Results 171 to 180 of about 127,735 (256)

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis. [PDF]

Iran J Basic Med Sci
Yuan J, Zhang R, Liu L, Ban YS, Qin C.
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

Structural and biochemical characterization of a glutathione transferase from the citrus canker pathogen Xanthomonas. [PDF]

Acta Crystallogr D Struct Biol, 2020
Hilario E, De Keyser S, Fan L.
europepmc   +1 more source

A Trp574–Leu substitution confers resistance to three classes of acetolactate synthase inhibitors in Australian brome grass (Bromus diandrus)

Pest Management Science, EarlyView.
Target‐site based imidazolinone resistance in brome grass was found to be conferred by a mutation at position 574 in the ALS gene and to severely impact the efficacy of the herbicide Intervix®, a co‐formulation of imazamox and imazapyr. Abstract BACKGROUND Brome grass (Bromus diandrus) is a prevalent weed in southern Australian cropping regions which ...
Roberto Busi, Danica Goggin, Nick Eyres, Fabian Runge, Aimone Porri, Ken Flower   +5 more
wiley   +1 more source

A Monocarbonyl Curcuminoid Derivative Inhibits the Activity of Human Glutathione Transferase A4-4 and Chemosensitizes Glioblastoma Cells to Temozolomide. [PDF]

Pharmaceuticals (Basel)
Tsouri S, Tselo E, Premetis GE, Furlan V, Pantiora PD, Mavroidi B, Matiadis D, Pelecanou M, Papageorgiou AC, Bren U, Sagnou M, Labrou NE.   +11 more
europepmc   +1 more source

Synergistic transition from type‐I‐like to type‐II‐like symptomology in a pyrethroid mixture and its impact on knockdown–mortality relationships in Musca domestica L

Pest Management Science, EarlyView.
In the present study, relationship between knockdown and mortality of insecticides was examined against the adult female housefly, Musca domestica. Type‐I pyrethroid insecticides showed a weak linkage, as early knocked down flies did not always result in mortality, while type‐II pyrethroids and organophosphates exhibited strong correlation between the ...
Junho Yoon, Jun‐Hyung Tak
wiley   +1 more source

Methylglyoxal Detoxification Revisited: Role of Glutathione Transferase in Model Cyanobacterium Synechocystis sp. Strain PCC 6803. [PDF]

mBio, 2020
Kammerscheit X, Hecker A, Rouhier N, Chauvat F, Cassier-Chauvat C.   +4 more
europepmc   +1 more source

Assessing the potential for insecticide cross‐resistance to a novel insecticide in the Colorado potato beetle (Leptinotarsa decemlineata) using phenotypic and transcript expression analysis

Pest Management Science, EarlyView.
Phenotypic and transcriptional responses to imidacloprid and isocycloseram were examined across U.S. populations of the Colorado potato beetle, showing evidence of phenotypic cross‐resistance alongside population‐level variation in detoxification gene expression.
Emma E. Terris, Benjamin Z. Bradford, Faith Kulzer, Justin Clements, Kurt H. Lamour, Sean D. Schoville, Russell L. Groves   +6 more
wiley   +1 more source