Results 11 to 20 of about 224,471 (305)

Glutathione Transferase (GST)-Activated Prodrugs

open access: yesPharmaceutics, 2013
Glutathione transferase (formerly GST) catalyzes the inactivation of various electrophile-producing anticancer agents via conjugation to the tripeptide glutathione.
Andrea Calderan, Paolo Ruzza
doaj   +1 more source

Plant Glutathione Transferases [PDF]

open access: yes, 2005
Soluble plant glutathione transferases (GSTs) consist of seven distinct classes, six of which have been functionally characterized. The phi and tau class GSTs are specific to plants and the most numerous and abundant of these enzymes. Both have classic conjugating activities toward a diverse range of xenobiotics, including pesticides, where they are ...
Robert, Edwards, David P, Dixon
openaire   +2 more sources

S-Denitrosylation: A Crosstalk between Glutathione and Redoxin Systems

open access: yesAntioxidants, 2022
S-nitrosylation of proteins occurs as a consequence of the derivatization of cysteine thiols with nitric oxide (NO) and is often associated with diseases and protein malfunction.
Surupa Chakraborty   +8 more
doaj   +1 more source

Glutathione transferase and mammary tumors

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2019
The analysis of publications from the last 5 years is presented in this review.  These articles describe the relationship of glutathione transferase (GST) with mammary tumors.
O. M. Fedets, I. M. Kurlyak
doaj   +1 more source

Differential activities of glutathione s-transferase isoenzymes in strains of fasciola hepatica susceptible and resistant to triclabendazole [PDF]

open access: yes, 2014
Fasciolosis, a parasitic zoonosis of intrahepatic location, is caused by the trematode Fasciola hepatica. Its control is mainly based on the use of the anthelminthic Triclabendazole (TCBZ).
Fernandez, Vanesa   +3 more
core   +1 more source

Glutathione s-transferase omega in the lung and sputum supernatants of COPD patients [PDF]

open access: yes, 2015
BACKGROUND: The major contribution to oxidant related lung damage in COPD is from the oxidant/antioxidant imbalance and possibly impaired antioxidant defence. Glutathione (GSH) is one of the most important antioxidants in human lung and lung secretions,
Board, Philip   +7 more
core   +1 more source

The expression of GST isoenzymes and p53 in non-small cell lung cancer.

open access: yesFolia Histochemica et Cytobiologica, 2010
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients.
MĂźzeyyen Ozhavzali   +6 more
doaj   +1 more source

Urinary felinine excretion in intact male cats is increased by dietary cystine [PDF]

open access: yes, 2008
Felinine is a branched-chain sulfur amino acid present in the urine of certain Felidae, including domestic cats. The objective of the present study was to determine if additional cystine and/or dietary N would increase felinine and N-acetylfelinine ...
Hendriks, W.H.   +4 more
core   +2 more sources

Does occupational exposure to solvents and pesticides in association with glutathione S-transferase A1, M1, P1, and T1 polymorphisms increase the risk of bladder cancer? The Belgrade case-control study.

open access: yesPLoS ONE, 2014
ObjectiveWe investigated the role of the glutathione S-transferase A1, M1, P1 and T1 gene polymorphisms and potential effect modification by occupational exposure to different chemicals in Serbian bladder cancer male patients.Patients and methodsA ...
Marija G Matic   +8 more
doaj   +1 more source

Role of G{alpha}12 and G{alpha}13 as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor [PDF]

open access: yes, 2007
G{alpha}12 and G{alpha}13 function as molecular regulators responding to extracellular stimuli. NF-E2-related factor 2 (Nrf2) is involved in a protective adaptive response to oxidative stress.
Cho, Min Kyung   +6 more
core   +2 more sources

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