Results 21 to 30 of about 127,735 (256)

Nitric oxide-mediated effects of L-ornithine-L-aspartate in acute toxic liver injury [PDF]

Pharmacia, 2022
This study was aimed to investigate nitric oxide-dependent mechanisms of L-ornithine-L-aspartate (LOLA) action in acute toxic liver injury in rats.
Vitalij Datsko, Halyna Loi, Tamara Datsko, Alla Mudra, Anna Mykolenko, Tetyana Golovata, Mykhailo Furdela, Yurii Orel, Iryna Smachylo, Andrii Burak, Mykola Klantsa, Oleksandra Oleshchuk   +11 more
doaj   +3 more sources

Glutathione transferase in helminths

Parasitology, 1990
The helminth glutathione (GSH) transferases are present as isoenzymes but fail to show a clear biochemical homology to any of the three mammalian GSH transferase families. GSH transferase is one of the major detoxification systems found in helminths, particularly high levels being found in cestodes and digeneans.
P M, Brophy, J, Barrett
openaire   +2 more sources

Glutathione S-Transferases in Cancer [PDF]

Antioxidants, 2021
In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities. GST proteins are crucial antioxidant enzymes that regulate stress-induced signaling pathways.
Rahul Raj Singh, Katie M. Reindl
openaire   +3 more sources

THE STATE OF GLUTATHIONE SYSTEM IN RAT TISSUES WITH TRAUMA MUSCULOSKELETAL SYSTEM IN THE METHIONINE INDUCED HYPERHOMOCYSTEINEMIA

Медицинский вестник Юга России, 2015
Purpose: to research the glutathione system state in rat tissues after trauma of the musculoskeletal system in a methionineinduced hyperhomocysteinemia.Materials and methods: the level of homocysteine in the plasma of animals, as well as the amount of ...
I. A. Alliluev, E. M. Vechkanov, I. A. Sorokina, Ju. N. Kaljuzhnaja, A. V. Temjakov, I. I. Kuznecov, V. V. Vnukov   +6 more
doaj   +1 more source

Reversal of hypermethylation and reactivation of glutathione -transferase pi 1 gene by curcumin in breast cancer cell line

Tumor Biology, 2017
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar, Ujjawal Sharma, Garima Rathi   +2 more
doaj   +1 more source

Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants

Plant Protection Science, 2004
Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it.
Lyuba P.-E. Miteva, Sergei V. Ivanov, Vera S. Alexieva, Emanuil N. Karanov   +3 more
doaj   +1 more source

Serum Paraoxonase, Arylesterase, and Glutathione-S-Transferase Activities and Oxidative Stress Levels in Patients with Mushroom Poisoning

Clinics, 2018
OBJECTIVES: Consumption of toxic species of mushrooms may have detrimental effects and increase oxidative stress. Paraoxonase, arylesterase and glutathione-S-transferase are antioxidants that resist oxidative stress.
Sevki Hakan Eren, Ilhan Korkmaz, Fatma Mutlu Kukul Guven, Yusuf Kenan Tekin, Levent Ozdemir   +4 more
doaj   +1 more source

Genetic polymorphisms of glutathione S-transferase Mu 1, glutathione S-transferase theta 1, and glutathione S-transferase P1 in oral squamous cell carcinoma: A case-control study in Iranian population

Journal of Orofacial Sciences, 2015
Background: Gene variability related to activation and detoxification of procarcinogens affects the susceptibility to oral squamous cell carcinoma (OSCC).
Bahram Yaghmaei, Kaveh Yaghmaei, Mohammad Jafarian, Shima Golmohammadi   +3 more
doaj   +1 more source

Reduction of MTT by Glutathione S-Transferase

BioTechniques, 1998
The reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to a blue formazan product is widely used for assaying cell survival and proliferation.
J.L. York, L.C. Maddox, P. Zimniak, T.E. McHugh, D.F. Grant   +4 more
doaj   +1 more source

Glutathione and glutathione S-transferases in Barrett's epithelium [PDF]

British Journal of Cancer, 1993
Glutathione content, enzyme activity and isoenzyme composition of glutathione S-transferases were assayed in normal and Barrett's esophageal epithelium of ten patients with Barrett's esophagus. In addition, gastric and duodenal specimens from the same patients were also investigated.
W H, Peters, H M, Roelofs, M P, Hectors, F M, Nagengast, J B, Jansen   +4 more
openaire   +2 more sources