Results 21 to 30 of about 224,471 (305)

Low serum glutathione-S-transferase activity and vitamin e levels do not correlate with disease severity in steady state adults with sickle cell anemia

Journal of Applied Hematology, 2017
Introduction: Adequate levels of antioxidants are essential in subjects with sickle cell anaemia (SCA) to counter the effects reactive oxygen species generated during normal red cell metabolism.
Patrick O Manafa, Chide E Okocha, John C Aneke, Ujunwa Obiano, Nancy C Ibeh, George O Chukwuma, Vera I Manafa   +6 more
doaj   +1 more source

GPI-anchored glutathione S-transferase as marker allows affinity sorting of transfection-positive cells

Frontiers in Molecular Biosciences, 2022
Cell transfection efficiency is still a limiting factor in gene function research. A method that allows isolation and enrichment of the transfection-positive cells is an effective solution. Here, we report a transfection-positive cell sorting system that
Shumin Ma, Lele Yang, Qingqing Zuo, Qilai Huang   +3 more
doaj   +1 more source

Glutathione transferases in bacteria [PDF]

The FEBS Journal, 2008
Bacterial glutathione transferases (GSTs) are part of a superfamily of enzymes that play a key role in cellular detoxification. GSTs are widely distributed in prokaryotes and are grouped into several classes. Bacterial GSTs are implicated in a variety of distinct processes such as the biodegradation of xenobiotics, protection against chemical and ...
ALLOCATI, Nerino, FEDERICI, Luca, MASULLI, Michele, DI ILIO, Carmine   +3 more
openaire   +2 more sources

Proteome readjustments in the apoplastic space of Arabidopsis thaliana ggt1 mutant leaves exposed to UV-B radiation [PDF]

, 2015
Ultraviolet-B radiation acts as an environmental stimulus, but in high doses it has detrimental effects on plant metabolism. Plasma membranes represent a major target for ROS generated by this harmful radiation.
ARRIGONI, GIORGIO, FABREGA PRATS, MARTA, GIARETTA, SABRINA, Leonard Ebinezer Barnabas, MASI, ANTONIO, PIVATO, MICAELA, PRASAD, DINESH, Syed M. M. Mehdi, TRENTIN, ANNA RITA   +8 more
core   +2 more sources

Metabolism of hydroperoxy-phospholipids in human hepatoma HepG2 cells

Journal of Lipid Research, 1996
Two enzymatic mechanisms have been proposed for the metabolism of hydroperoxy-phospholipids: i) the combined action of phospholipase A2 and glutathione peroxidase, and/or ii) direct enzymatic reduction.
Y Bao, G Williamson
doaj   +1 more source

Nitric oxide-mediated effects of L-ornithine-L-aspartate in acute toxic liver injury [PDF]

Pharmacia, 2022
This study was aimed to investigate nitric oxide-dependent mechanisms of L-ornithine-L-aspartate (LOLA) action in acute toxic liver injury in rats.
Vitalij Datsko, Halyna Loi, Tamara Datsko, Alla Mudra, Anna Mykolenko, Tetyana Golovata, Mykhailo Furdela, Yurii Orel, Iryna Smachylo, Andrii Burak, Mykola Klantsa, Oleksandra Oleshchuk   +11 more
doaj   +3 more sources

Leaf apoplastic proteome composition in UV-B treated Arabidopsis thaliana mutants impaired in extracellular glutathione degradation [PDF]

, 2016
In plants, environmental perturbations often result in oxidative reactions in the apoplastic space, which are counteracted for by enzymatic and non-enzymatic antioxidative systems, including ascorbate and glutathione. The occurrence of the latter and its
Arrigoni, Giorgio, Masi, Antonio, Trentin, ANNA RITA   +2 more
core   +1 more source

THE STATE OF GLUTATHIONE SYSTEM IN RAT TISSUES WITH TRAUMA MUSCULOSKELETAL SYSTEM IN THE METHIONINE INDUCED HYPERHOMOCYSTEINEMIA

Медицинский вестник Юга России, 2015
Purpose: to research the glutathione system state in rat tissues after trauma of the musculoskeletal system in a methionineinduced hyperhomocysteinemia.Materials and methods: the level of homocysteine in the plasma of animals, as well as the amount of ...
I. A. Alliluev, E. M. Vechkanov, I. A. Sorokina, Ju. N. Kaljuzhnaja, A. V. Temjakov, I. I. Kuznecov, V. V. Vnukov   +6 more
doaj   +1 more source

The genetics of cardiovascular disease [PDF]

, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero, Aitman, Anna F. Dominiczak, Benhamou, Bhatnagar, Bowcock, Caulfield, Chen, Christian Delles, Clark, Conrad, Cowley, Cupples, Delles, Delles, Delles, Dominiczak, Dominiczak, Dutil, Edwards, Emilsson, Garrett, Good, Graham, Grunfeld, Gunderson, Guzik, Hamilton, Hamilton, Harrap, Hunt, Iwai, Jakubowska, Jeffs, Jeffs, Ji, Kathiresan, Kerr, Klein, Latronico, Levy, Martin W. McBride, Matarín, Matarín, Matsuzaki, McBride, McBride, McCarthy, Monti, Moreno, Mueller, Newhouse, Oniki, Padmanabhan, Padmanabhan, Petretto, Pollex, Rapp, Roodi, Samani, Sandhu, Sandosh Padmanabhan, Sayed-Tabatabaei, Sharma, Staessen, Teo, Tobin, Tobin, Turner, Wallace, Wilson, Zalba, Zimmerli   +72 more
core   +1 more source

Reversal of hypermethylation and reactivation of glutathione -transferase pi 1 gene by curcumin in breast cancer cell line

Tumor Biology, 2017
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar, Ujjawal Sharma, Garima Rathi   +2 more
doaj   +1 more source