Results 31 to 40 of about 148,506 (307)
Glutathione transferase in helminths
The helminth glutathione (GSH) transferases are present as isoenzymes but fail to show a clear biochemical homology to any of the three mammalian GSH transferase families. GSH transferase is one of the major detoxification systems found in helminths, particularly high levels being found in cestodes and digeneans.
P M, Brophy, J, Barrett
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Glutathione S-Transferases in Cancer [PDF]
In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities. GST proteins are crucial antioxidant enzymes that regulate stress-induced signaling pathways.
Rahul Raj Singh, Katie M. Reindl
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Purpose: to research the glutathione system state in rat tissues after trauma of the musculoskeletal system in a methionineinduced hyperhomocysteinemia.Materials and methods: the level of homocysteine in the plasma of animals, as well as the amount of ...
I. A. Alliluev +6 more
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One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar +2 more
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Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it.
Lyuba P.-E. Miteva +3 more
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Nitric oxide-mediated effects of L-ornithine-L-aspartate in acute toxic liver injury [PDF]
This study was aimed to investigate nitric oxide-dependent mechanisms of L-ornithine-L-aspartate (LOLA) action in acute toxic liver injury in rats.
Vitalij Datsko +11 more
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Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate [PDF]
Epidemiological studies suggest that people who consume more than one portion of cruciferous vegetables per week are at lower risk of both the incidence of prostate cancer and of developing aggressive prostate cancer but there is little understanding of ...
Richard Y Ball +36 more
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OBJECTIVES: Consumption of toxic species of mushrooms may have detrimental effects and increase oxidative stress. Paraoxonase, arylesterase and glutathione-S-transferase are antioxidants that resist oxidative stress.
Sevki Hakan Eren +4 more
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Background: Gene variability related to activation and detoxification of procarcinogens affects the susceptibility to oral squamous cell carcinoma (OSCC).
Bahram Yaghmaei +3 more
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Reduction of MTT by Glutathione S-Transferase
The reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to a blue formazan product is widely used for assaying cell survival and proliferation.
J.L. York +4 more
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